Evidence map›Paper›PMID 30805394›Full record

ArticleReports of biochemistry & molecular biology2019

The Influence of Gamma Radiation Processing on the Allergenicity of Main Pistachio Allergens.

Vahid Yaghoubi Naei, Mojtaba Sankian, Malihe Moghadam, Narges Farshidi, Seyed Hasan Ayati, Fatemeh Hamid, Abdol-Reza Varasteh

Abstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Vahid Yaghoubi NaeiImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.
Mojtaba SankianImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.
Malihe MoghadamImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.
Narges FarshidiImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.
Seyed Hasan AyatiImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.
Fatemeh HamidDepartment of Medical Laboratory, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Abdol-Reza VarastehImmunology Research Center, Bu-Ali Research Institute, University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGamma irradiation is a form of processing with an array of applications in medical sciences such as microbial decontamination, viruses inactivation, cervical carcinoma and breast cancer treatment. One of the ways in which gamma irradiation has the potential to be used is in reducing the allergenicity of food allergens.

methodsIn the present study, pistachios were irradiated with either a 1, 10, or 100 kGy dose of gamma irradiation. The binding rate of mice and human antibodies to the allergens of the pistachio extracts were examined via Western blot analysis.

resultsOur findings show an inverse dose-response relationship between the binding rate of antibodies to the pistachio allergens and the gamma irradiation dose. Despite these promising findings, the results of our sensory evaluation indicate that gamma irradiation causes undesirable changes to the sensory characteristics of pistachios, especially at the dose of 100 kGy.

conclusionGamma irradiation appears to be an effective method in reducing the allergenicity of pistachios. Thus, this form of processing has the potential to prevent adverse allergic reactions to the major pistachio allergens in sensitized subjects. However, further research must be dedicated to examining the dose sufficient in reducing allergencity, while maintaining adequate sensory quality for satisfactory consumption.

Indexed as

AllergenicityGamma irradiationPistachio

Identifiers

PMID30805394
PMCPMC6374055

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