Evidence map›Paper›PMID 30805374›Full record

ArticleJournal of immunology research2019

Shared Medical and Environmental Risk Factors in Dry Eye Syndrome, Sjogren's Syndrome, and B-Cell Non-Hodgkin Lymphoma: A Case-Control Study.

Hadas Ben-Eli, Doron J Aframian, Eldad Ben-Chetrit, Dror Mevorach, Geffen Kleinstern, Ora Paltiel, Abraham Solomon

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Epidemiology of Sjögren syndrome.Nature reviews. Rheumatology · 2024
    Review
  7. Review
  8. Review
  9. B-Cell NHL Subtype Risk Associated with Autoimmune Conditions and PRS.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hadas Ben-EliBraun School of Public Health and Community Medicine, Hadassah-Hebrew University of Jerusalem, Israel.ORCID 0000-0002-2832-4221
Doron J AframianDepartment of Oral Medicine, Sedation and Maxillofacial Imaging and Sjogren's Syndrome Center, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Eldad Ben-ChetritUnit of Rheumatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Dror MevorachDepartment of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Geffen KleinsternBraun School of Public Health and Community Medicine, Hadassah-Hebrew University of Jerusalem, Israel.
Ora PaltielBraun School of Public Health and Community Medicine, Hadassah-Hebrew University of Jerusalem, Israel.
Abraham SolomonDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Hadassah Medical Center · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess whether there are shared exposures associated with Sjogren's syndrome (SS), dry eye syndrome (DES), and B-cell non-Hodgkin lymphoma (B-NHL), in order to determine whether they are etiologically related.

methodsIn a clinic-based case-control study, 702 participants (91 SS, 120 DES, 211 (age and sex frequency-matched) controls, and 280 B-NHL cases) were recruited and interviewed regarding exposures, medical history, and family history.

resultsFemale predominance was noted in SS (ratio 9.2 : 1). Eye dryness was severest in SS compared to DES and controls (

conclusionsSome exposures are associated with all three conditions (such as an inverse association with alcohol consumption and a positive association with serious past infection), while a family history of AID appears to be shared by DES and SS, but not NHL subjects. Shared risk factors for all three conditions indicate possible mutual etiological pathways.

Indexed as

EnvironmentAdultAgedCase-Control StudiesDry Eye SyndromesFemaleHealth BehaviorHumansLymphoma, B-CellMaleMedical History TakingMiddle AgedOdds RatioRisk FactorsSex FactorsSjogren's Syndrome

Identifiers

PMID30805374
PMCPMC6360537
OpenAlexW2909393719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.