Evidence map›Paper›PMID 30805369›Full record

ArticleBioMed research international2019

Relationships of

Shimin Hu, Shujuan Ma, Xun Li, Zhengwen Tian, Huiling Liang, Junxia Yan, Mengshi Chen, Hongzhuan Tan

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  8. Article
  9. Genetic and Epigenetic Factors in Gestational Diabetes Mellitus Pathology.International journal of molecular sciences · 2023
    Review
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  15. Article
  16. Replication of previous genome-wide association studies ofDiabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shimin HuSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.ORCID 0000-0002-3284-2494
Shujuan MaSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.
Xun LiDepartment of Obstetrics and Gynecology, Xiangya Hospital of Central South University, 87 Xiangya Road, Changsha, Hunan, China.
Zhengwen TianSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.
Huiling LiangSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.
Junxia YanSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.
Mengshi ChenSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.
Hongzhuan TanSchool of Public Health, Central South University, 90 Xiangya Road, Changsha, Hunan, China.ORCID 0000-0002-4292-5947
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSolute carrier family 2 member 4- (SLC2A4-) retinol binding protein-4- (RBP4-) phosphoenolpyruvate carboxykinase 1 (PCK1)/phosphoinositide 3-kinase (PI3K) is an adipocyte derived "signalling pathway" that may contribute to the pathogenesis of type 2 diabetes mellitus (T2DM). We explored whether single nucleotide polymorphisms (SNPs) of these "signalling pathway" genes are associated with gestational diabetes mellitus (GDM).

methodsCase-control studies were conducted to compare GDM and control groups. A total of 334 cases and 367 controls were recruited. Seventeen candidate SNPs of the pathway were selected. Chi-square tests, logistic regression, and linear regression were used to estimate the relationships of SNPs with GDM risk and oral glucose tolerance test (OGTT), fasting insulin, and homeostasis model assessment of insulin resistance (HOMA-IR) levels. Model-based multifactor dimensionality reduction was used to estimate the adjusted interactions between genes. Regression and interaction analyses were adjusted by maternal age, prepregnancy BMI, and weekly BMI growth. The Bonferroni correction was applied for multiple comparisons.

results

conclusion

Indexed as

AdultAsian PeopleBlood GlucoseCase-Control StudiesDiabetes, GestationalDiabetes Mellitus, Type 2FemaleGenetic Predisposition to DiseaseGenotypeGlucose Transporter Type 4HumansInsulinInsulin ResistanceIntracellular Signaling Peptides and ProteinsPhosphatidylinositol 3-KinasesPhosphoenolpyruvate Carboxykinase (GTP)Blood GlucoseGlucose Transporter Type 4InsulinIntracellular Signaling Peptides and ProteinsPCK1 protein, humanPhosphatidylinositol 3-KinasesPhosphoenolpyruvate Carboxykinase (GTP)RBP4 protein, humanRetinol-Binding Proteins, PlasmaSLC2A4 protein, human

Identifiers

PMID30805369
PMCPMC6363241
OpenAlexW2908890299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.