Evidence map›Paper›PMID 30804990›Full record

ArticleNeural plasticity2019

Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice.

Gayane Grigoryan, Niklas Lonnemann, Martin Korte

Abstract read
In one paragraph

Article in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gayane GrigoryanDivision of Cellular Neurobiology, Zoological Institute, Technical University of Braunschweig, Braunschweig 38106, Germany.ORCID 0000-0001-9754-4730
Niklas LonnemannDivision of Cellular Neurobiology, Zoological Institute, Technical University of Braunschweig, Braunschweig 38106, Germany.
Martin KorteDivision of Cellular Neurobiology, Zoological Institute, Technical University of Braunschweig, Braunschweig 38106, Germany.ORCID 0000-0001-6956-5913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal stress (PS) has long-term sequelae for the morphological and functional status of the central nervous system of the progeny. A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. We addressed here the question of how PS-induced alterations in the immune response in young and old mice may contribute to changes in hippocampal function in aging. Immune stimulation (via

Indexed as

Adrenergic NeuronsAnimalsCorticosteroneFemaleHippocampusLipopolysaccharidesLong-Term PotentiationMiceNeuronal PlasticityPregnancyPrenatal Exposure Delayed EffectsStress, PsychologicalCorticosteroneLipopolysaccharides

Identifiers

PMID30804990
PMCPMC6360630

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.