Evidence map›Paper›PMID 30804925›Full record

ArticleFrontiers in immunology2019

Thymic Function as a Predictor of Immune Recovery in Chronically HIV-Infected Patients Initiating Antiretroviral Therapy.

Rita Rb-Silva, Claudia Nobrega, Cecilia Azevedo, Emilia Athayde, João Canto-Gomes, Ivo Ferreira, Rémi Cheynier, Andrew J Yates, Ana Horta, Margarida Correia-Neves

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  16. Performance assessment of 11 commercial serological tests for SARS-CoV-2 on hospitalised COVID-19 patients.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  17. Review
  18. Inflammatory Phenotypes Predict Changes in Arterial Stiffness Following Antiretroviral Therapy Initiation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Rita Rb-SilvaPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Claudia NobregaPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Cecilia AzevedoDepartment of Mathematics and Applications, School of Sciences, University of Minho, Braga, Portugal.
Emilia AthaydeDepartment of Mathematics and Applications, School of Sciences, University of Minho, Braga, Portugal.
João Canto-GomesPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Ivo FerreiraPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Rémi CheynierINSERM, U1016, Institut Cochin, Paris, France.
Andrew J YatesDepartment of Pathology & Cell Biology, Columbia University, New York, NY, United States.
Ana HortaPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Margarida Correia-NevesPopulation Health Research Domain, Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
University of Minho · PTCentre National de la Recherche Scientifique · FRCentro Hospitalar do Porto · PTColumbia University · USInstituto Português de Oncologia Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor immunological responders (PIR) are HIV-infected patients with virologic suppression upon antiretroviral therapy (ART) but persistently low CD4

Indexed as

AdultAge FactorsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4-CD8 RatioCD4 Lymphocyte CountCD4-Positive T-LymphocytesFemaleHIV-1HIV InfectionsHumansImmunophenotypingLymphocyte ActivationMaleMiddle AgedReceptors, Antigen, T-CellAnti-HIV AgentsReceptors, Antigen, T-Cellantiretroviral therapyCD4+ T cellsHIV infectionimmune activationimmune recoverypoor immunological responderspredictive modelingthymic function

Identifiers

PMID30804925
PMCPMC6370619
OpenAlexW2914834573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.