Evidence map›Paper›PMID 30804772›Full record

ReviewFrontiers in human neuroscience2019

A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD).

Yuyang Luo, Dana Weibman, Jeffrey M Halperin, Xiaobo Li

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06064032 (Comparing The Effects Of Cognitive Behavioral Therapy And Motor Learning Technique in Adults With Attention Deficit Hyperactivity Disorder.), which is not on this map. Cited by 172 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 6 pooled it
24.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06064032 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparing The Effects Of Cognitive Behavioral Therapy And Motor Learning Technique in Adults With Attention Deficit Hyperactivity Disorder.

TypeinterventionalSponsorShalamar Institute of Health SciencesRan2023 to 2023Enrolled36ConditionsAttention Deficit Hyperactivity DisorderArmscognitive behavioral therapy, Motor Learning Techniques
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 6 syntheses or guidelines pooled it, 377 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Patterns of Early Development in Children with ADHD.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
    Article

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuyang LuoDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States.
Dana WeibmanDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States.
Jeffrey M HalperinDepartment of Psychology, Queens College of the City University of New York, Flushing, NY, United States.
Xiaobo LiDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States.
New Jersey Institute of Technology · USQueens College, CUNY · US

Funding

Translational Neuroimaging CoreP30HD071593 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WALKLEY, STEVEN UPSHAW · 2011 to 2015
$5.6M
Neuroanatomical markers of persistence versus remission of ADHDR03MH109791 · NIMH · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI LI, XIAOBO · 2016 to 2017
$154k
NICHD NIH HHS P30 HD071593NIMH NIH HHS R03 MH109791
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects approximately 8%-12% of children worldwide. Throughout an individual's lifetime, ADHD can significantly increase risk for other psychiatric disorders, educational and occupational failure, accidents, criminality, social disability and addictions. No single risk factor is necessary or sufficient to cause ADHD. The multifactorial causation of ADHD is reflected in the heterogeneity of this disorder, as indicated by its diversity of psychiatric comorbidities, varied clinical profiles, patterns of neurocognitive impairment and developmental trajectories, and the wide range of structural and functional brain anomalies. Although evidence-based treatments can reduce ADHD symptoms in a substantial portion of affected individuals, there is yet no curative treatment for ADHD. A number of theoretical models of the emergence and developmental trajectories of ADHD have been proposed, aimed at providing systematic guides for clinical research and practice. We conducted a comprehensive review of the current status of research in understanding the heterogeneity of ADHD in terms of etiology, clinical profiles and trajectories, and neurobiological mechanisms. We suggest that further research focus on investigating the impact of the etiological risk factors and their interactions with developmental neural mechanisms and clinical profiles in ADHD. Such research would have heuristic value for identifying biologically homogeneous subgroups and could facilitate the development of novel and more tailored interventions that target underlying neural anomalies characteristic of more homogeneous subgroups.

Indexed as

ADHDcognitive impairmentsDTIfunctional MRIheterogeneityneuroscience modelrisk factorsstructural MRI

Identifiers

PMID30804772
PMCPMC6378275
OpenAlexW2914917294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.