Evidence map›Paper›PMID 30804703›Full record

ArticleTropical medicine and health2019

Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People's Democratic Republic.

Yukako Kaneshiro, Khamphang Sourinphoumy, Naoki Imaizumi, Mangkhalar Rasaphon, Megumi Kuba-Miyara, Shugo Sakihama, Carmina Louise Hugo Guerrero, Ketsaphone Nhativong, Daisuke Nonaka, Tiengkham Pongvongsa and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Yukako Kaneshiro1Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Khamphang SourinphoumySavannakhet Provincial Hospital, Savannakhet, Lao People's Democratic Republic.
Naoki Imaizumi3Laboratory of Molecular Genetics, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Mangkhalar RasaphonSavannakhet Provincial Hospital, Savannakhet, Lao People's Democratic Republic.
Megumi Kuba-Miyara1Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Shugo Sakihama4Department of Pathology and Cell Biology, Graduate School of Medicine, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa Japan.
Carmina Louise Hugo Guerrero1Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Ketsaphone NhativongSavannakhet Provincial Health Department, Savannakhet, Lao People's Democratic Republic.
Daisuke Nonaka6Department of Global Health, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Tiengkham PongvongsaSavannakhet Provincial Health Department, Savannakhet, Lao People's Democratic Republic.
Jun Kobayashi6Department of Global Health, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
Sengchanh Kounnavong7National Institute of Public Health, Vientiane, Lao People's Democratic Republic.
Takuya Fukushima1Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.
University of the Ryukyus · JPPublic Health Department · INNational Institute of Public Health · LA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Lao People's Democratic Republic (PDR), which borders China, Vietnam, Cambodia, Thailand, and Myanmar, the number of HIV-infected patients has increased in recent years. HIV-infected patients diagnosed in Lao PDR are enrolled in a registration network and receive antiretroviral therapy (ART) covered by governmental financial support. Based on the registration network, we investigated intestinal helminth infections and coinfection with HTLV-1 in HIV-infected patients treated with an early intervention using ART in Lao PDR.

methodsThis cross-sectional study of all 252 HIV-infected patients at Savannakhet Provincial Hospital, located in the southern part of Lao PDR, was conducted between February and March 2018. Socioepidemiological information and clinical information were collected from a registration network database and by questionnaire administered to participants. Microscopic examination of intestinal helminth infections in stool samples and particle agglutination for anti-HTLV-1 antibody in plasma were performed.

resultsThe median age of all 252 participants was 39 years old (range, 18-59). Based on the registration network database, there were 156 (61.9%) HIV-infected patients with a CD4-positive cell count ≥ 200 cells/μL and 146 (57.9%) with an HIV viral load < 250 copies/mL. Among 212 stool samples, 75 (35.4%) were found to contain one or more intestinal helminth species, including

conclusionThe registration network and an early intervention using ART may provide good medical care and improve the clinical course of HIV-infected patients in Lao PDR. However, the incidence of intestinal helminth infections remains high at 35.4%. The development of a specific medical care system for helminth infection for HIV-infected patients is necessary.

Indexed as

Helminth infectionsHuman immunodeficiency virusHuman T cell leukemia virus type ILao People’s Democratic RepublicRegistration network

Identifiers

PMID30804703
PMCPMC6371529
OpenAlexW2920950301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.