ArticleNature ecology & evolution2019
Antarctic blackfin icefish genome reveals adaptations to extreme environments.
Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 173 citations in OpenAlex.
- Genomic Signatures of Selection Are Enriched in Differentially Expressed Genes in Sticklebacks Adapting to Contrasting Environments.Genome biology and evolution · 2026Article
- Convergent latitudinal erosion of circadian systems in a rapidly diversifying order of fishes.PLoS genetics · 2026Article
- Chromosome-scale genome assembly and annotation of Jonah's icefish Neopagetopsis ionah.Scientific data · 2026Article
- Truncated Life History Underlies Rapid Local Adaptation in Island Rattlesnake Venom Expression.Genome biology and evolution · 2026Article
- Superoxide Dismutase 3 Deficiency Disrupts the Regulation of Oxidative Stress Caused by Polystyrene Nanoplastics.Antioxidants (Basel, Switzerland) · 2025Article
- Hemoglobin-Gene Cluster Deletions in Antarctic White-Blooded Icefishes Facilitated by Transposable Elements.Genome biology and evolution · 2025Article
- Intron turnover of slc26a1 and slc26a2 and convergence of intron insertion sites.Scientific reports · 2025Article
- Sex Differentiation and Long-Distance Gene Flow in the Elusive Antarctic FishEcology and evolution · 2025Article
- Identification and Functional Analysis of a Key Gene in the CHH Gene Family for Glucose Metabolism in the Pacific White ShrimpInternational journal of molecular sciences · 2025Article
- Genomic, transcriptomic and epigenomic signatures of ageing and cold adaptation in the Antarctic clamOpen biology · 2025Article
- The interplay between epigenomic and transcriptomic variation during ecotype divergence in stickleback.BMC biology · 2025Article
- Twenty-First-Century Environmental Change Decreases Habitat Overlap of Antarctic Toothfish (Dissostichus mawsoni) and Its Prey.Global change biology · 2025Article
- The genome of the cryopelagic Antarctic bald notothen, Trematomus borchgrevinki.G3 (Bethesda, Md.) · 2025Article
- Klumpy: A tool to evaluate the integrity of long-read genome assemblies and illusive sequence motifs.Molecular ecology resources · 2025Article
- The macroevolutionary dynamics of pharyngognathy in fishes fail to support the key innovation hypothesis.Nature communications · 2024Article
- Chromosome-level genome assembly and annotation of the Patagonian toothfish Dissostichus eleginoides.Scientific data · 2024Article
- De novo assembly and annotation of the Patagonian toothfish (Dissostichus eleginoides) genome.BMC genomics · 2024Article
- An Antarctic lichen isolate (Cladonia borealis) genome reveals potential adaptation to extreme environments.Scientific reports · 2024Article
- Chromosome-level genome assembly and annotation of the Antarctica whitefin plunderfish Pogonophryne albipinna.Scientific data · 2023Article
- Cold-Driven Hemoglobin Evolution in Antarctic Notothenioid Fishes Prior to Hemoglobin Gene Loss in White-Blooded Icefishes.Molecular biology and evolution · 2023Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
22 authors at 6 institutions in 3 countries.
Funding
Abstract
Icefishes (suborder Notothenioidei; family Channichthyidae) are the only vertebrates that lack functional haemoglobin genes and red blood cells. Here, we report a high-quality genome assembly and linkage map for the Antarctic blackfin icefish Chaenocephalus aceratus, highlighting evolved genomic features for its unique physiology. Phylogenomic analysis revealed that Antarctic fish of the teleost suborder Notothenioidei, including icefishes, diverged from the stickleback lineage about 77 million years ago and subsequently evolved cold-adapted phenotypes as the Southern Ocean cooled to sub-zero temperatures. Our results show that genes involved in protection from ice damage, including genes encoding antifreeze glycoprotein and zona pellucida proteins, are highly expanded in the icefish genome. Furthermore, genes that encode enzymes that help to control cellular redox state, including members of the sod3 and nqo1 gene families, are expanded, probably as evolutionary adaptations to the relatively high concentration of oxygen dissolved in cold Antarctic waters. In contrast, some crucial regulators of circadian homeostasis (cry and per genes) are absent from the icefish genome, suggesting compromised control of biological rhythms in the polar light environment. The availability of the icefish genome sequence will accelerate our understanding of adaptation to extreme Antarctic environments.
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