Evidence map›Paper›PMID 30804200›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity.

Smita Yadav, Susan H Younger, Linghua Zhang, Katherine L Thompson-Peer, Tun Li, Lily Y Jan, Yuh Nung Jan

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Glial-derived TNF/Eiger signaling promotes somatosensory neurite sculpting.Cellular and molecular life sciences : CMLS · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Drosophila glia take shape to sculpt the nervous system.Current opinion in neurobiology · 2023
    Review
  10. Article
  11. Article
  12. A photo-switchable assay system for dendrite degeneration and repair inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Smita YadavDepartment of Physiology, University of California, San Francisco, CA 94158.ORCID 0000-0002-5228-9235
Susan H YoungerDepartment of Physiology, University of California, San Francisco, CA 94158.
Linghua ZhangThe Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Katherine L Thompson-PeerDepartment of Physiology, University of California, San Francisco, CA 94158.ORCID 0000-0002-4200-3870
Tun LiDepartment of Physiology, University of California, San Francisco, CA 94158.
Lily Y JanDepartment of Physiology, University of California, San Francisco, CA 94158.ORCID 0000-0003-1367-6299
Yuh Nung JanDepartment of Physiology, University of California, San Francisco, CA 94158; Yuhnung.jan@ucsf.edu.
Howard Hughes Medical Institute · USJohns Hopkins University · US

Funding

Dendrite morphogenesis, function and regenerationR35NS097227 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, YUH NUNG · 2017 to 2024
$5.1M
Role of Autism Susceptibility Gene, TAOK2 kinase, and its novel substrates in SynaptogenesisR00MH108648 · NIMH · UNIVERSITY OF WASHINGTON · PI YADAV, SMITA · 2018 to 2020
$745k
Role of Autism Susceptibility Gene, TAOK2 kinase, and its novel substrates in SynaptogenesisK99MH108648 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YADAV, SMITA · 2015 to 2016
$242k
Mechanisms of Dendrite Regeneration after InjuryK99NS097627 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMPSON-PEER, KATHERINE LOUISE · 2016 to 2017
$198k
NIMH NIH HHS K99 MH108648NIMH NIH HHS R00 MH108648NINDS NIH HHS K99 NS097627NINDS NIH HHS R35 NS097227
6 · The paper itself

Abstract

Sensory neurons perceive environmental cues and are important of organismal survival. Peripheral sensory neurons interact intimately with glial cells. While the function of axonal ensheathment by glia is well studied, less is known about the functional significance of glial interaction with the somatodendritic compartment of neurons. Herein, we show that three distinct glia cell types differentially wrap around the axonal and somatodendritic surface of the polymodal dendritic arborization (da) neuron of the

Indexed as

AnimalsAxonsCaspasesDendritesDNA HelicasesDrosophila melanogasterDrosophila ProteinsEnzyme ActivationLightNeurogliaSensory Receptor CellsCaspasesDNA HelicasesDrosophila ProteinsXNP protein, DrosophilaATRXglia–neuron interactionsensory neurons

Identifiers

PMID30804200
PMCPMC6421456
OpenAlexW2917974708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.