Evidence map›Paper›PMID 30804197›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Redox and pH gradients drive amino acid synthesis in iron oxyhydroxide mineral systems.

Laura M Barge, Erika Flores, Marc M Baum, David G VanderVelde, Michael J Russell

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 198 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Mineral-facilitated aqueous synthesis of hydrogen cyanide from prebiotically abundant amino acids for chemical evolution.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Review
  7. FeNature communications · 2025
    Article
  8. Article
  9. Article
  10. Primitive homochiral polyester formation driven by tartaric acid and calcium availability.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Electricity in the Creation of Life.Reviews of physiology, biochemistry and pharmacology · 2025
    Review
  14. Glycine synthesis from nitrate and glyoxylate mediated by ferroan brucite: An integrated pathway for prebiotic amine synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Unraveling abiotic organic synthesis pathways in the mafic crust of mid-ocean ridges.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Laura M BargeNASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109; laura.m.barge@jpl.nasa.gov.
Erika FloresNASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109.
Marc M BaumDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016.
David G VanderVeldeDepartment of Chemistry, California Institute of Technology, Pasadena, CA 91125.
Michael J RussellNASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109.
Jet Propulsion Laboratory · USCalifornia Institute of Technology · USOak Crest Institute of Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron oxyhydroxide minerals, known to be chemically reactive and significant for elemental cycling, are thought to have been abundant in early-Earth seawater, sediments, and hydrothermal systems. In the anoxic Fe

Indexed as

early Earthgradientshydrothermal ventsiron hydroxideslife emergence

Identifiers

PMID30804197
PMCPMC6421445
OpenAlexW2917196427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.