Evidence map›Paper›PMID 30804146›Full record

ArticleIn vivo (Athens, Greece)

Postoperative Level of C-Reactive Protein Is a Prognosticator After Esophageal Cancer Surgery With Perioperative Steroid Therapy and Enhanced Recovery After Surgery Care.

Kazuki Kano, Toru Aoyama, Yukio Maezawa, Tsutomu Hayashi, Takanobu Yamada, Hiroshi Tamagawa, Tsutomu Sato, Haruhiko Cho, Takaki Yoshikawa, Yasushi Rino and 3 more

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Effect of Diabetes Mellitus on Prognosis of Patients with Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2020
    Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kazuki Kano *Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan.
Toru Aoyama *Department of Surgery, Yokohama City University, Kanagawa, Japan.
Yukio MaezawaDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Tsutomu HayashiDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan.
Takanobu YamadaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan.
Hiroshi TamagawaDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Tsutomu SatoDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Haruhiko ChoDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Takaki YoshikawaDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Yasushi RinoDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Munetaka MasudaDepartment of Surgery, Yokohama City University, Kanagawa, Japan.
Takashi OshimaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan oshimat@kcch.jp ogatat@kcch.jp.
Takashi OgataDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan oshimat@kcch.jp ogatat@kcch.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated the impact of postoperative C-reactive protein (CRP) level on survival in patients with esophageal cancer who received perioperative steroid therapy and enhanced recovery after surgery (ERAS) care. PATIENTS AND

methodsOverall, 115 patients were retrospectively reviewed. The patients were classified into those with a high CRP level (≥4.0 mg/dl) on postoperative day 4 and those with low CRP level (<4.0 mg/dl). The risk factors for overall survival (OS) and recurrence-free survival (RFS) were identified.

resultsThe OS and RFS rates at 5 years after surgery were significantly low in patients with high CRP level on postoperative day 4. The multivariate analysis demonstrated that high CRP level on postoperative day 4 was a significant independent risk factor for OS and RFS.

conclusionThe present results suggest that the postoperative CRP level can be a prognosticator in patients with esophageal cancer who have received perioperative steroid therapy and ERAS care.

Indexed as

AgedCefazolinC-Reactive ProteinEsophageal NeoplasmsFemaleHumansMaleMiddle AgedPerioperative CarePostoperative PeriodPrognosisSteroidsCefazolinC-Reactive ProteinSteroidsC-reactive proteinenhanced recovery after surgery carePostoperativesteroid therapy

Identifiers

PMID30804146
PMCPMC6506316

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.