Evidence map›Paper›PMID 30804107›Full record

ArticleIn vivo (Athens, Greece)

Malignant Transformation of Fanconi Anemia Complementation Group D2-deficient (

Xichen Zhang, Renee Fisher, Donna Shields, Wen Hou, Darcy Franicola, Hong Wang, Michael W Epperly, Lora Rigatti, Joel S Greenberger

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xichen ZhangDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Renee FisherDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Donna ShieldsDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Wen HouDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Darcy FranicolaDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Hong WangDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Michael W EpperlyDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Lora RigattiDepartment of Veterinary Medicine, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Joel S GreenbergerDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A. greenbergerjs@upmc.edu.
UPMC Hillman Cancer Center · USUniversity of Pittsburgh · USUPMC Health System · US

Funding

Training and EducationU19AI068021 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENBERGER, JOEL S · 2005 to 2019
$44.4M
NIAID NIH HHS U19 AI068021
6 · The paper itself

Abstract

aimTo demonstrate that Fanconi anemia complementation group D2-deficient (Fancd2 MATERIALS AND

methodsIn order to determine whether a single HPV type 16 (HPV16) oncogene induced malignant transformation, Fancd2

resultsFancd2

conclusionA single HPV16 oncogene is adequate to produce malignant transformation of Fancd2

Indexed as

Cell Line, TumorCell Transformation, NeoplasticFanconi Anemia Complementation Group D2 ProteinHematopoietic Stem CellsHuman papillomavirus 16HumansInterleukin-3Oncogene Proteins, ViralOncogenesPapillomavirus E7 ProteinsPlasmidsRepressor ProteinsTransfectionE6 protein, Human papillomavirus type 16FANCD2 protein, humanFanconi Anemia Complementation Group D2 ProteinIL3 protein, humanInterleukin-3oncogene protein E7, Human papillomavirus type 16Oncogene Proteins, ViralPapillomavirus E7 ProteinsRepressor ProteinsE6 and E7 oncogeneFanconi anemiaHuman Papillomavirus

Identifiers

PMID30804107
PMCPMC6506306
OpenAlexW2916994719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.