ReviewIn vivo (Athens, Greece)
Oxidative Stress and Oral Mucosal Diseases: An Overview.
Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Oxidative stress and antioxidant markers in oral leukoplakia: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Atrophy and Inflammatory Changes in Salivary Glands Induced by Oxidative Stress after Exposure to Drugs and Other Chemical Substances: A Systematic Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Unlocking Potential ofGels (Basel, Switzerland) · 2026Article
- Effect of intraoral and extraoral photobiomodulation on salivary oxidative stress and inflammatory cytokines in patients with radiotherapy-induced oral mucositis.Scientific reports · 2026Article
- Zinc-Containing Surgical Stents for Soft Tissue Healing: Clinical Case Series and Chair-Side Application.Reports (MDPI) · 2026Article
- The Role of Cellular Senescence in Oral Health and Disease.International journal of molecular sciences · 2026Review
- Salivary Oxidative Stress and Antioxidant Markers in Oral Leukoplakia: A Systematic Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2026Review
- Key Early Changes in Oral Squamous Cell Carcinogenesis Are Accelerated by Ectopic BMI1 Expression.Cancer research communications · 2026Article
- Salivary proteins, proteases, and disease pathophysiology in oral health and precision diagnostics: a narrative review.Frontiers in dental medicine · 2026Review
- The effect of Hippophae rhamnoides on Hydroxychloroquine-Induced stomatitis in rats.BMC complementary medicine and therapies · 2025Article
- Harnessing Polymeric Dissolvable Microneedles: Precision Delivery of Therapeutics for Oral Ulcers.ACS omega · 2025Review
- The study of the therapeutic effect and preliminary mechanism of EGCG on recurrent aphthous ulcer.Scientific reports · 2025Article
- Thiol-disulfide parameters in recurrent aphthous stomatitis: A cross-sectional study.BMC oral health · 2025Article
- Evaluation of Oxidative Stress Markers in Post-Surgical Head and Neck Cancer Patients Rehabilitated with Removable Prosthetic Restorations.Antioxidants (Basel, Switzerland) · 2025Article
- Oral Gel Formulation ofPharmaceutics · 2025Article
- Cell Proliferation, DNA Damage, and Apoptosis in Oral Leukoplakia and Oral Squamous Cell Carcinoma in Young Patients: A Comparative Immunohistochemical Study.Head and neck pathology · 2025Article
- Clinical and Microbiological Study on Local Application of an Ozonated Olive Oil Gel in the Periodontal Pockets: A Randomized Double-Blind Trial.Journal of clinical medicine · 2025Article
- Balancing the Oral Redox State: Endogenous and Exogenous Sources of Reactive Oxygen Species and the Antioxidant Role of Lamiaceae and Asteraceae.Dentistry journal · 2025Review
- Association Between Ethylene Oxide Exposure and Complete Edentulism in United States Adults.Life (Basel, Switzerland) · 2025Article
- Huangqi Baihe Granules Attenuate Hypobaric Hypoxia-Induced Brain Injury via HIF-1a/p53/Caspase-3 Pathway.Drug design, development and therapy · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReactive oxygen species (ROS) and free radicals are physiologically produced during cellular metabolism. When their balance is disrupted in favor of ROS, a condition called oxidative stress occurs. Oxidative stress represents a widespread phenomenon involved in several pathological conditions. The aim of the present review was to report current knowledge on oxidative stress related to oral mucosal diseases. MATERIALS AND
methodsArticles from 2000 to 2018 were selected for relevance, validity and quality, from results obtained in PubMed, MEDLINE and Google Scholar using the following search terms: oxidative stress and oral lichen, oral pemphigus, aphthous stomatitis, oral leukoplakia, oral cancer, oral squamous cell carcinoma and oral carcinoma. All articles were independently screened for eligibility by the authors.
resultsThis narrative review integrates extensive information from all relevant published studies focusing on oxidative stress in oral mucosal diseases. We outline the pathogenetic function of oxidative stress in the most frequent inflammatory, potentially malignant and malignant diseases of the oral mucosa and provide detailed findings from human research.
conclusionAlthough variability in findings between individual studies exists, it justifies the conclusion that oxidative stress is a significant process in the oral mucosal diseases pathogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.