Evidence map›Paper›PMID 30804096›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

A Resting-State Functional MR Imaging and Spectroscopy Study of the Dorsal Hippocampus in the Chronic Unpredictable Stress Rat Model.

Ricardo Magalhães, Ashley Novais, David A Barrière, Paulo Marques, Fernanda Marques, João C Sousa, João J Cerqueira, Arnaud Cachia, Therese M Jay, Michel Bottlaender and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. to extrapolation of primary absorbed compounds as multifunctional proxies of Zhiqiao ()-Houpo () herb pair.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
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  8. Continuous Ingestion ofInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Ricardo MagalhãesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal, id5832@alunos.uminho.pt.ORCID 0000-0001-6279-2195
Ashley NovaisLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-6392-8090
David A BarrièreNeuroSpin, CEA, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.ORCID 0000-0003-4355-3329
Paulo MarquesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Fernanda MarquesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
João C SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
João J CerqueiraLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Arnaud CachiaInserm U894, Center for Psychiatry and Neurosciences, Université Paris-Descartes, 75014 Paris, France.ORCID 0000-0003-2125-4985
Therese M JayInserm U894, Center for Psychiatry and Neurosciences, Université Paris-Descartes, 75014 Paris, France.ORCID 0000-0002-2468-1141
Michel BottlaenderNeuroSpin, CEA, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.ORCID 0000-0002-2890-3653
Nuno SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-8755-5126
Sébastien MériauxNeuroSpin, CEA, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.ORCID 0000-0001-7430-8348
Fawzi BoumezbeurNeuroSpin, CEA, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.ORCID 0000-0002-3786-1053
University of Minho · PTCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRDélégation Paris 5 · FRClinical Academic Center of Braga · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to chronic stress leads to an array of anatomical, functional, and metabolic changes in the brain that play a key role in triggering psychiatric disorders such as depression. The hippocampus is particularly well known as a target of maladaptive responses to stress. To capture stress-induced changes in metabolic and functional connectivity in the hippocampus, stress-resistant (low-responders) or -susceptible (high-responders) rats exposed to a chronic unpredictable stress paradigm (categorized according to their hormonal and behavioral responses) were assessed by multimodal neuroimaging; the latter was achieved by using localized

Indexed as

AnimalsChronic DiseaseDisease Models, AnimalHippocampusMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleRandom AllocationRatsRats, WistarRestStress, PsychologicalfMRIfunctional connectivityhippocampusMRSresistance and susceptibilitystress

Identifiers

PMID30804096
PMCPMC6510342
OpenAlexW2917467869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.