Evidence map›Paper›PMID 30804007›Full record

ArticleArchives of disease in childhood2020

Vitamin D supplementation: are multivitamins sufficient?

Rebecca J Moon, Elizabeth M Curtis, Cyrus Cooper, Justin H Davies, Nicholas C Harvey

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Analytical Bias in the Measurement of Plasma 25-Hydroxyvitamin D Concentrations in Infants.International journal of environmental research and public health · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecca J MoonMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Southampton, UK.
Elizabeth M CurtisMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Southampton, UK.
Cyrus CooperMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Southampton, UK.
Justin H DaviesPaediatric Endocrinology, Southampton University Hospitals NHS Foundation Trust, Southampton, UK.
Nicholas C HarveyMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Southampton, UK.

Funding

Department of Health 10/33/04Department of Health HTA/10/33/04Medical Research Council G0400491Medical Research Council G0601019Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Versus Arthritis 17702Versus Arthritis 21231Wellcome Trust 201222/Z/16/Z
6 · The paper itself

Abstract

backgroundPublic Health England advises 400 IU/day vitamin D supplementation for children over 1 year. Commercially available children's multivitamin and vitamin D supplements were surveyed to determine the vitamin D content.

methodsMultivitamins and vitamin D supplements marketed at children <12 years and sold by nine UK supermarkets and health supplement retailers were surveyed. Vitamin D content was determined from manufacturer's websites and product packaging.

results67 multivitamins were surveyed, containing 0-800 IU/day vitamin D. Only 25%-36%, depending on the child's age, provided ≥400 IU/day vitamin D. Supplements containing only vitamin D or labelled as for 'healthy bones' typically had higher vitamin D content (57%-67% contained ≥400 IU/day).

conclusionsFew multivitamin products supply the recommended 400 IU/day vitamin D. Clinicians need to be aware of this when recommending vitamin D supplementation and advise parents/carers to choose a product that contains ≥400 IU/day vitamin D.

Indexed as

Dietary SupplementsRecommended Dietary AllowancesVitamin DVitaminsChildChild, PreschoolHumansInfantInfant, NewbornUnited KingdomVitamin DVitaminsdietary supplementationmultivitaminricketsVitamin D

Identifiers

PMID30804007
PMCPMC7115846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.