Evidence map›Paper›PMID 30804004›Full record

ArticleThe EMBO journal2019

Histidine is selectively required for the growth of Myc-dependent dedifferentiation tumours in the

Francesca Froldi, Panayotis Pachnis, Milán Szuperák, Olivia Costas, Tharindu Fernando, Alex P Gould, Louise Y Cheng

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Nonautonomous Regulation of Tumor Growth.Advances in experimental medicine and biology · 2025
    Review
  5. Review
  6. Ribosome stalling duringPNAS nexus · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Tumor models in various Drosophila tissues.WIREs mechanisms of disease · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Francesca FroldiPeter MacCallum Cancer Centre, Parkville, Vic., Australia.
Panayotis PachnisThe Francis Crick Institute, London, UK.
Milán SzuperákPeter MacCallum Cancer Centre, Parkville, Vic., Australia.
Olivia CostasPeter MacCallum Cancer Centre, Parkville, Vic., Australia.
Tharindu FernandoThe Francis Crick Institute, London, UK.
Alex P GouldThe Francis Crick Institute, London, UK.
Louise Y ChengPeter MacCallum Cancer Centre, Parkville, Vic., Australia louise.cheng@petermac.org.ORCID 0000-0001-9712-4082
The Francis Crick Institute · GBThe University of Melbourne · AUPeter MacCallum Cancer Centre · AU

Funding

Medical Research Council MC_U117533887Medical Research Council MC_U117584237Wellcome Trust FC001088
6 · The paper itself

Abstract

Rewired metabolism of glutamine in cancer has been well documented, but less is known about other amino acids such as histidine. Here, we use

Indexed as

Cell DedifferentiationAnimalsCentral Nervous System NeoplasmsDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsFemaleHistidineHistidine DecarboxylaseMaleNeural Stem CellsTranscription FactorsDNA-Binding ProteinsDrosophila ProteinsHistidineHistidine DecarboxylaseMyc protein, Drosophilanerfin-1 protein, DrosophilaTranscription FactorsdedifferentiationDrosophilahistidinemetabolismneuroblast

Identifiers

PMID30804004
PMCPMC6443203
OpenAlexW2917849170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.