Evidence map›Paper›PMID 30803987›Full record

ArticleThe Journal of biological chemistry2019

An α

Jian Jing, Yanna Sun

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jian JingFrom the Beijing Key Laboratory of Genetic Engineering and Biotechnology, College of Life Sciences, Beijing Normal University, Xinwai St. 19, Haidian District, Beijing 100875, China jjing@bnu.edu.cn.
Yanna SunFrom the Beijing Key Laboratory of Genetic Engineering and Biotechnology, College of Life Sciences, Beijing Normal University, Xinwai St. 19, Haidian District, Beijing 100875, China.
Beijing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood platelets are required for normal wound healing, but they are also involved in thrombotic diseases, which are usually managed with anticoagulant drugs. Here, using genetic engineering, we coupled the disintegrin protein echistatin, which specifically binds to the platelet integrin α

Indexed as

AnimalsAnnexin A5Blood CoagulationEscherichia coliHumansIntercellular Signaling Peptides and ProteinsMaleMicePhosphatidylserinesPlatelet AggregationPlatelet Glycoprotein GPIIb-IIIa ComplexProtein BindingRecombinant Fusion ProteinsThrombosisAnnexin A5echistatinIntercellular Signaling Peptides and ProteinsPhosphatidylserinesPlatelet Glycoprotein GPIIb-IIIa ComplexRecombinant Fusion Proteinsannexindrug designfusion proteinphosphatidylserineprotein chimeraprotein engineeringprotein expressionprotein–lipid interactionprotein motifthrombosis

Identifiers

PMID30803987
PMCPMC6497940
OpenAlexW2916508081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.