Evidence map›Paper›PMID 30803886›Full record

Trial reportRespiratory medicine2019

Characteristics at the time of oxygen initiation associated with its adherence: Findings from the COPD Long-term Oxygen Treatment Trial.

Marilyn L Moy, Kathleen F Harrington, Alice L Sternberg, Jerry A Krishnan, Richard K Albert, David H Au, Richard Casaburi, Gerard J Criner, Philip Diaz, Richard E Kanner and 8 more

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Respiratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Marilyn L MoyPulmonary and Critical Care Medicine Section, VA Boston Healthcare System and Harvard Medical School, Boston, MA, USA. Electronic address: marilyn.moy@va.gov.
Kathleen F HarringtonDivision of Pulmonary, Allergy and Critical Care Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Alice L SternbergDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Jerry A KrishnanUniversity of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Richard K AlbertUniversity of Colorado School of Medicine, Aurora, CO, USA.
David H AuVeterans Affairs Puget Sound Health Care System and University of Washington, Seattle, WA, USA.
Richard CasaburiRehabilitation Clinical Trials Center, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Gerard J CrinerLewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Philip DiazPulmonary, Allergy, Critical Care, and Sleep Medicine Division, Ohio State University, Columbus, OH, USA.
Richard E KannerDivision of Pulmonary Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
Ralph J PanosCincinnati Veterans Affairs Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Thomas StiboltKaiser Permanente Center for Health Research, Portland, OR, USA.
James K StollerCleveland Clinic, Cleveland, OH, USA.
James TonasciaDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Roger D YusenDivision of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USA.
Ai-Yui M TanDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Anne L FuhlbriggeUniversity of Colorado School of Medicine, Aurora, CO, USA.
LOTT Research Group

Funding

NHLBI NIH HHS N01 HR076197
6 · The paper itself

Abstract

rationaleCharacteristics associated with adherence to long-term oxygen therapy (LTOT) in COPD remain unclear.

objectivesTo identify patient characteristics at the time of oxygen initiation associated with its adherence.

methodsWe conducted a secondary analysis of data from 359 COPD participants assigned to oxygen in the Long-term Oxygen Treatment Trial. Participants were prescribed continuous (n = 214) or intermittent (n = 145) oxygen based on desaturation patterns at study entry. At the time of initial prescription, participants rated their perceived readiness, confidence, and importance to use oxygen on a 0-10 scale (0 = not at all, 10 = very much). During follow-up, they self-reported average hours per day of use (adherence). Adherence was averaged over short-term (0-30 days), medium-term (months 9-12), and long-term (month 13 to last follow-up) intervals. Multivariable logistic regression models explored characteristics associated with high adherence (≥16 h/day [continuous] or ≥8 h/day [intermittent]) during each time interval.

resultsParticipant readiness, confidence, and importance at the time of oxygen initiation were associated with high short- and medium-term adherence. For each unit increase in baseline readiness, the odds of high short-term adherence increased by 21% (odds ratio [OR] 1.21, 95% confidence interval [CI] 1.05-1.40) and 94% (OR 1.94, 95% CI 1.45-2.59) in the continuous and intermittent groups, respectively. In both groups, high adherence in the medium-term was associated with high adherence in the long-term (continuous, OR 12.49, 95% CI 4.90-31.79; intermittent, OR 38.08, 95% CI 6.96-208.20).

conclusionsReadiness, confidence, and importance to use LTOT at initiation, and early high adherence, are significantly associated with long-term oxygen adherence.

Indexed as

AftercareAgedDisease ProgressionEarly Intervention, EducationalFemaleHumansHypoxiaMaleMiddle AgedOutcome Assessment, Health CareOxygen Inhalation TherapyPerceptionPulmonary Disease, Chronic ObstructiveSelf ConceptSelf EfficacyTimeAdherenceConfidenceCOPDLTOTReadinessSelf-efficacy

Identifiers

PMID30803886
PMCPMC6424633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.