Evidence map›Paper›PMID 30803442›Full record

ArticleBMC nephrology2019

Influenza vaccination among children with idiopathic nephrotic syndrome: an investigation of practices.

Roman Klifa, Julie Toubiana, Alizée Michel, Nathalie Biebuyck, Marina Charbit, Laurence Heidet, Saoussen Krid, Pauline Krug, Rémi Salomon, Olivia Boyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Varicella vaccination in children with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  4. Article
  5. Vaccines and nephrotic syndrome: efficacy and safety.Pediatric nephrology (Berlin, Germany) · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roman KlifaNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France. klifaroman@msn.com.ORCID 0000-0002-3957-1359
Julie ToubianaPédiatrie Générale et Infectieuse, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, Paris, France.
Alizée MichelNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Nathalie BiebuyckNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Marina CharbitNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Laurence HeidetNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Saoussen KridNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Pauline KrugNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Rémi SalomonNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.
Olivia BoyerNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de l'enfant et l'adulte, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne paris Cité, 149 rue de Sèvres, 75015, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnnual influenza vaccination is recommended for all children with idiopathic nephrotic syndrome (INS) in France. Consequently, the Social Security automatically sends prescriptions to all patients suffering from a chronic disease. The aim of this study was to evaluate the follow-up to these recommendations.

methodsWe conducted a monocentric retrospective investigation of practices. We included all children with steroid-sensitive INS in remission who attended our clinics from January 1st 2015 to January 1st 2017, resided in France and had a valid phone number. Data were collected from May 2017 to June 2017 through a phone interview and review of clinical charts.

results75 patients met the inclusion criteria. The parents of 57 children could be reached by phone and agreed to participate to the survey. 35/57 (61.4%) declared having received a prescription during the 2016-2017 campaign. Only 14 children (24.6%) were vaccinated. 17/43 (39.5%) parents of unvaccinated children had concerns about the safety of the vaccine, 16/43 (37.2%) were not aware of the recommendations, 5/43 (11.6%) had been recommended by their physician not to vaccinate their child, 3/43 (7%) forgot to have them vaccinated and 2/43 (4.6%) reported no reason. 13/43 (30%) unvaccinated children presented a relapse during the flu season - 2/13 during an influenza-like illness - whereas 1/14 (7%) immunized children presented a relapse during the six months of post-vaccination follow-up. Relapse rates were not increased in vaccinated children compared to unvaccinated children (p = 0.15), nor in the 6 months following vaccination compared to the 6 months prior (1/14 vs 5/14, p = 0.20).

conclusions1) < 2/3 patients were properly prescribed the recommended yearly influenza vaccination at our center 2) only 1/4 were vaccinated and most of their parents were misinformed. Physicians must be aware of this and should make every effort to better inform their patients on the risks of flu illness and the benefits and safety of the vaccination.

Indexed as

Influenza, HumanNephrotic SyndromePatient Care ManagementProfessional-Family RelationsVaccinationChildCommunication BarriersFemaleFranceHumansInfluenza VaccinesMaleNeeds AssessmentOutcome and Process Assessment, Health CareRetrospective StudiesTreatment Adherence and ComplianceInfluenza VaccinesEfficacyIdiopathic nephrotic syndromeInfluenzaPracticesSafetyVaccination

Identifiers

PMID30803442
PMCPMC6388483

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.