Evidence map›Paper›PMID 30803281›Full record

ArticleJournal of the American Heart Association2019

Thrombectomy in Childhood Stroke.

Peter B Sporns, André Kemmling, Uta Hanning, Jens Minnerup, Ronald Sträter, Thomas Niederstadt, Walter Heindel, Moritz Wildgruber

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Case report of ischemic stroke in a child secondary to neuroborreliosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Article
  4. Non-routine thrombectomy in pediatric arterial ischemic stroke.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
    Article
  5. Four cases of mechanical thrombectomy in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Childhood stroke.Nature reviews. Disease primers · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Pediatric internal carotid artery dissection and stroke after minor head injury.Journal of the American College of Emergency Physicians open · 2021
    Article
  17. Endovascular treatment of pediatric ischemic stroke: A single center experience and review of the literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Peter B Sporns1 Institute of Clinical Radiology University Hospital of Muenster Germany.
André Kemmling1 Institute of Clinical Radiology University Hospital of Muenster Germany.
Uta Hanning3 Department of Diagnostic and Interventional Neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Jens Minnerup4 Department of Neurology University of Muenster Germany.
Ronald Sträter5 Department of Pediatrics University of Muenster Germany.
Thomas Niederstadt1 Institute of Clinical Radiology University Hospital of Muenster Germany.
Walter Heindel1 Institute of Clinical Radiology University Hospital of Muenster Germany.
Moritz Wildgruber1 Institute of Clinical Radiology University Hospital of Muenster Germany.
University Hospital Münster · DEAugenstern · DEUniversität Hamburg · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Several randomized trials have shown the efficacy of thrombectomy for large intracranial vessel occlusions in adults. However, the safety and efficacy of thrombectomy in children are unknown. We aimed to investigate the feasibility and outcome of thrombectomy in pediatric patients. Methods and Results We performed a retrospective analysis of all children (<18 years of age) who presented with large-vessel occlusion and were treated with mechanical thrombectomy at 3 German tertiary-care stroke centers. Interventional results and clinical outcomes were assessed using the Pediatric National Institutes of Health Stroke Scale at 24 hours and on day 7 after thrombectomy as well as after 3 months (modified Rankin Scale). After screening of local registries for all performed thrombectomies, 12 children were included. Median Pediatric National Institutes of Health Stroke Scale score on admission was 12.5 (interquartile range 8.0-21.5). Angiographic outcomes for thrombectomy were good in all patients (6×modified Treatment in Cerebral Infarction Score 3, 6×modified Treatment in Cerebral Infarction Score 2b). Moreover, most patients showed an improvement of neurological outcome after thrombectomy with a median Pediatric National Institutes of Health Stroke Scale of 3.5 (interquartile range 1-8) at day 7 and a modified Rankin Scale of 1.0 (interquartile range 0-2.0) at 3 months. No major periprocedural complications were observed. Conclusions In our retrospective study thrombectomy was safe in childhood stroke, and treated children had good neurological outcomes.

Indexed as

ThrombectomyAdolescentAge of OnsetBrain IschemiaCerebral AngiographyChildChild, PreschoolDisability EvaluationFeasibility StudiesFemaleGermanyHumansMaleRecovery of FunctionRetrospective StudiesStrokechildhood strokeendovascular recanalizationischemic strokepediatric strokethrombectomy

Identifiers

PMID30803281
PMCPMC6474928
OpenAlexW2916358774

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.