ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2019
Reduced focal fiber collinearity in the cingulum bundle in adults with obsessive-compulsive disorder.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring functional connectivity in large-scale brain networks in obsessive-compulsive disorder: a systematic review of EEG and fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- Associations among mediodorsal thalamic-ventrolateral prefrontal cortical white matter fiber dispersion and OCD-related incompleteness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Medial prefrontal-thalamic white matter microstructure is associated with harm avoidance in OCD: a discovery and transdiagnostic replication study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Widespread alterations of white matter integrity in medication-free obsessive-compulsive disorder.Translational psychiatry · 2025Article
- Examining relationships among NODDI indices of white matter structure in prefrontal cortical-thalamic-striatal circuitry and OCD symptomatology.Translational psychiatry · 2024Article
- Prefrontal-Limbic Circuitry Is Associated With Reward Sensitivity in Nonhuman Primates.Biological psychiatry · 2024Article
- Structural Connectivity Reorganization Based on DTI after Cingulotomy in Obsessive-Compulsive Disorder.Brain sciences · 2022Article
- Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth.Translational psychiatry · 2022Article
- Segmental abnormalities of superior longitudinal fasciculus microstructure in patients with schizophrenia, bipolar disorder, and attention-deficit/hyperactivity disorder: An automated fiber quantification tractography study.Frontiers in psychiatry · 2022Article
- Four Deep Brain Stimulation Targets for Obsessive-Compulsive Disorder: Are They Different?Biological psychiatry · 2021Review
- White matter microstructural and Compulsive Sexual Behaviors Disorder - Diffusion Tensor Imaging study.Journal of behavioral addictions · 2021Review
- An association of Myelin Oligodendrocyte Glycoprotein (MOG) gene variants with white matter volume in pediatric obsessive-compulsive disorder.Psychiatry research. Neuroimaging · 2021Article
- Nonhuman primate meso-circuitry data: a translational tool to understand brain networks across species.Brain structure & function · 2021Review
- Tract Specific White Matter Lesion Load Affects White Matter Microstructure and Their Relationships With Functional Connectivity and Cognitive Decline.Frontiers in aging neuroscience · 2021Article
- Diffusion Tensor Imaging Before and 3 Months After Concentrated Exposure Response Prevention in Obsessive-Compulsive Disorder.Frontiers in psychiatry · 2021Article
- The Role of Self-Talk in Predicting Death Anxiety, Obsessive-Compulsive Disorder, and Coping Strategies in the Face of Coronavirus Disease (COVID-19).Iranian journal of psychiatry · 2020Article
- A nonlinear relationship of evoked responses following charge-balanced single-pulse electrical stimulation with varying pulse widths.Brain stimulationArticle
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Obsessive-compulsive disorder (OCD) is a disabling condition, often associated with a chronic course. Given its role in attentional control, decision-making, and emotional regulation, the anterior cingulate cortex is considered to have a key role in the pathophysiology of the disorder. Notably, the cingulum bundle, being the major white matter tract connecting to this region, has been historically a target for the surgical treatment of intractable OCD. In this study, we aimed to identify the extent to which focal-more than diffuse-abnormalities in fiber collinearity of the cingulum bundle could distinguish 48 adults with OCD (mean age [SD] = 23.3 [4.5] years; F/M = 30/18) from 45 age- and sex-matched healthy control adults (CONT; mean age [SD] = 23.2 [3.8] years; F/M = 28/17) and further examine if these abnormalities correlated with symptom severity. Use of tract-profiles rather than a conventional diffusion imaging approach allowed us to characterize white matter microstructural properties along (100 segments), as opposed to averaging these measures across, the entire tract. To account for these 100 different segments of the cingulum bundle, a repeated measures analysis of variance revealed a main effect of group (OCD < CONT; F
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.