ArticleJournal of affective disorders2019
Trajectories of depression and anxiety symptom change during psychological therapy.
Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 87 citations in OpenAlex.
- A Randomized Controlled Trial Comparing Group Transdiagnostic Behavior Therapy (TBT) and Group Disorder-Specific Psychotherapies in Veterans With Emotional Disorders.Journal of clinical psychology · 2026Trial
- Symptom Trajectories in Patients With Anxiety Disorders During Transdiagnostic Cognitive Behavioral Therapy.Depression and anxiety · 2026Trial
- Effects of Transdiagnostic Cognitive Behavioural Therapy on Long-Term Quality of Life: A Causal Mediation Analysis Across Anxiety and Depressive Symptoms.Depression and anxiety · 2026Trial
- Depression and weight loss trajectories during an integrated behavioral intervention: Within-treatment analysis of the RAINBOW trial.PloS one · 2025Trial
- Trajectories of perinatal depression among women living with HIV in Uganda.Journal of global health · 2024Trial
- Long-term depressive symptom trajectories and related baseline characteristics in primary care patients: Analysis of the PsicAP clinical trial.European psychiatry : the journal of the Association of European Psychiatrists · 2024Trial
- Trajectories of Symptom Change in School-Based Prevention Programs for Adolescent Girls with Subclinical Depression.Journal of youth and adolescence · 2022Trial
- Psychotherapy is not just for Rich White People: Outcomes for Clients from Minoritized Backgrounds and in a Community Training Clinic.Journal of racial and ethnic health disparities · 2026Article
- Identifying distinct trajectories of change in anhedonia during psychological treatment for depression.Psychological medicine · 2026Article
- Uncovering latent trajectories of daily tinnitus symptoms through app-based monitoring during treatment.Internet interventions · 2026Article
- Observational
- The Digital Mental Health Study assessed feasibility of large-scale digital sensing for depression and anxiety.npj digital public health · 2026Article
- Association of the sarcopenia index with incident depressive symptoms and adverse depressive symptom trajectories.Frontiers in nutrition · 2026Article
- Association between the combination of GABAergic agents and SSRIs at the first clinical visit and depressive symptom trajectories: A study using group-based trajectory modeling and Apriori algorithm.PLOS mental health · 2026Article
- Patient and course of care factors impacting time to response and remission in psychotherapy for depression.Frontiers in psychology · 2026Article
- Assessing Heterogeneity in Sentiment Changes in Text-Based Counseling: Latent Class Trajectory Analysis.Journal of medical Internet research · 2025Article
- Article
- Influence and Predictors of Anxiety on Health Status ≥ 5 Years Beyond Breast Cancer Diagnosis in Spain: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Long-term depressive symptoms trajectories following CBT delivered in primary care compared to usual treatment.Psychological medicine · 2024Article
- Longitudinal trajectories of symptom change during antidepressant treatment among managed care patients with depression and anxiety.Npj mental health research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundForty-percent of the variance in psychological treatment outcomes is estimated to be explained by symptom change by the third treatment session. However, change may not be uniform across patient groups and symptom domains. This study aimed to identify subgroups of patients with different trajectories of depression and anxiety symptom change during psychological therapy and identify baseline patient characteristics associated with these trajectories.
methods4394 patients attending two psychological treatment services completed sessional, self-report depression and anxiety measures. Trajectories of symptom change were investigated using latent class growth analysis. Multinomial logistic regression was used to explore associations between baseline patient characteristics and trajectory classes.
resultsA number of distinct trajectories were identified. Anxiety symptom trajectories could be distinguished by the third treatment session, but for depression symptoms there was a class displaying limited change until session six followed by rapid improvement in symptoms thereafter. Compared to the non-responding trajectories, depression and anxiety trajectories indicating treatment response were associated with lower baseline severity, better social functioning and lower incidence of phobic anxiety, but not with medication prescription status. LIMITATIONS: Data came from two services, so wider generalisability is unknown. Predictors were limited to data routinely collected in the services; unmeasured factors may have improved the prediction of trajectories.
conclusionsBaseline characteristics and symptom change early in therapy can help identify different trajectories of symptom change. This knowledge could aid clinical decision making and help improve treatment outcomes. By ignoring distinct trajectories, clinicians may incorrectly consider patients as "not-on-track" and unnecessarily change or end therapy that would otherwise benefit patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.