Evidence map›Paper›PMID 30802685›Full record

ReviewBiomaterials2019

Designing next generation of photon upconversion: Recent advances in organic triplet-triplet annihilation upconversion nanoparticles.

Ling Huang, Eugenia Kakadiaris, Tereza Vaneckova, Kai Huang, Marketa Vaculovicova, Gang Han

Abstract readReview
In one paragraph

Review in Biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Upconversion Nanostructures Applied in Theranostic Systems.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Photon Upconversion Hydrogels for 3D Optogenetics.Advanced functional materials · 2021
    Article
  16. Article
  17. Chemical science · 2020
    Article
  18. Multifaceted aspects of charge transfer.Physical chemistry chemical physics : PCCP · 2020
    Article
  19. Triplet-Triplet Annihilation Upconversion in a MOF with Acceptor-Filled Channels.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ling HuangDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States.
Eugenia KakadiarisDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States.
Tereza VaneckovaDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States; Department of Chemistry and Biochemistry Mendel University in Brno, Brno, 61300, Czech Republic.
Kai HuangDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States.
Marketa VaculovicovaDepartment of Chemistry and Biochemistry Mendel University in Brno, Brno, 61300, Czech Republic.
Gang HanDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States. Electronic address: Gang.Han@umassmed.edu.

Funding

NanoOptogenetic immunotherapy for B cell lymphomaR01CA232017 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HAN, GANG, ZHOU, YUBIN · 2019 to 2023
$2.2M
Wireless Optogenetics by relay nano-illuminatorsR01MH103133 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HAN, GANG · 2013 to 2016
$1.3M
Optogenetic toolkit for remote control of voltage-gated calcium channelsR21GM126532 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HAN, GANG, ZHOU, YUBIN · 2018 to 2019
$443k
NCI NIH HHS R01 CA232017NIGMS NIH HHS R21 GM126532NIMH NIH HHS R01 MH103133
6 · The paper itself

Abstract

Organic triplet-triplet annihilation upconversion (TTA-UC) nanoparticles have emerged as exciting therapeutic agents and imaging probes in recent years due to their unique chemical and optical properties such as outstanding biocompatibility and low power excitation density. In this review, we focus on the latest breakthroughs in such new version of upconversion nanoparticle, including their design, preparation, and applications. First, we will discuss the key principles and design concept of these organic-based photon upconversion in regard to the methods of selection of the related triplet TTA dye pairs (photosensitizer and emitter). Then, we will discuss the recent approaches s to construct TTA-UCNPs including silica TTA-UCNPs, lipid-coated TTA-UCNPs, polymer encapsulated TTA-UCNPs, nano-droplet TTA-UCNPs and metal-organic frameworks (MOFs) constructed TTA-UCNPs. In addition, the applications of TTA-UCNPs will be discussed. Finally, we will discuss the challenges posed by current TTA-UCNP development.

Indexed as

Diagnostic ImagingMolecular StructureNanoparticlesPolymersSilicon DioxidePolymersSilicon DioxideAnd cancer therapyBioimagingNanoparticlesPhoto-targetingTriplet-triplet annihilation upconversion

Identifiers

PMID30802685
PMCPMC6467534

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.