ArticlePloS one2019
Soleus muscle weakness in cerebral palsy: Muscle architecture revealed with Diffusion Tensor Imaging.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Effects of progressive functional ankle exercises in spastic cerebral palsy, plantarflexors versus dorsiflexors: a randomized trial.Turkish journal of medical sciences · 2023Trial
- Subject-specific muscle properties from diffusion tensor imaging significantly improve the accuracy of musculoskeletal models.Journal of anatomy · 2020Trial
- Overcoming pitfalls in multi-stack diffusion MRI for tractography reconstruction of skeletal muscles.Scientific reports · 2026Article
- Physiological Cross-Sectional Surfaces: A Method for Estimating Muscle Functional Capacity from 3D Digital Models of Fiber Architecture.bioRxiv : the preprint server for biology · 2026Article
- Statistical Shape and Fibre Orientation Model for Muscle Architecture Characterisation of the Medial Gastrocnemius.Annals of biomedical engineering · 2025Article
- Quantifying structural properties of forearm flexor muscles in individuals with hemiparetic cerebral palsy using diffusion tensor imaging.Physiological reports · 2025Article
- Imaging and Image Processing Techniques for High-Resolution Visualization of Connective Tissue with MRI: Application to Fascia, Aponeurosis, and Tendon.Journal of imaging · 2025Article
- Changes to muscle and fascia tissue after eighteen days of ankle immobilization post-ankle sprain injury: an MRI case study.BMC musculoskeletal disorders · 2025Article
- Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments.Frontiers in endocrinology · 2025Article
- Diffusion tensor imaging reveals subclinical alterations in muscles of patients with Becker muscular dystrophy.The British journal of radiology · 2024Article
- Accelerated IVIM-corrected DTI in acute hamstring injury: towards a clinically feasible acquisition time.European radiology experimental · 2024Article
- Sensitivity analyses of probabilistic and deterministic DTI tractography methodologies for studying arm muscle architecture.Magnetic resonance in medicine · 2024Article
- Clinical applications of skeletal muscle diffusion tensor imaging.Skeletal radiology · 2023Review
- A statistical shape model of soleus muscle morphology in spastic cerebral palsy.Scientific reports · 2022Article
- Muscle architecture, growth, and biological Remodelling in cerebral palsy: a narrative review.BMC musculoskeletal disorders · 2022Review
- Development of DTI Based Probabilistic Tractography Methods to Characterize Arm Muscle Architecture in Individuals Post Hemiparetic Stroke.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021Article
- High Inter-Rater Reliability of Manual Segmentation and Volume-Based Tractography in Healthy and Dystrophic Human Calf Muscle.Diagnostics (Basel, Switzerland) · 2021Article
- A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy.Frontiers in bioengineering and biotechnology · 2021Article
- Correction: Soleus muscle weakness in cerebral palsy: Muscle architecture revealed with Diffusion Tensor Imaging.PloS one · 2020Article
- In vivo muscle morphology comparison in post-stroke survivors using ultrasonography and diffusion tensor imaging.Scientific reports · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral palsy (CP) is associated with movement disorders and reduced muscle size. This latter phenomenon has been observed by computing muscle volumes from conventional MRI, with most studies reporting significantly reduced volumes in leg muscles. This indicates impaired muscle growth, but without knowing muscle fiber orientation, it is not clear whether muscle growth in CP is impaired in the along-fiber direction (indicating shortened muscles and limited range of motion) or the cross-fiber direction (indicating weak muscles and impaired strength). Using Diffusion Tensor Imaging (DTI) we can determine muscle fiber orientation and construct 3D muscle architectures which can be used to examine both along-fiber length and cross-sectional area. Such an approach has not been undertaken in CP. Here, we use advanced DTI sequences with fast imaging times to capture fiber orientations in the soleus muscle of children with CP and age-matched, able-bodied controls. Cross sectional areas perpendicular to the muscle fiber direction were reduced (37 ± 11%) in children with CP compared to controls, indicating impaired muscle strength. Along-fiber muscle lengths were not different between groups. This study is the first to demonstrate along-fiber and cross-fiber muscle architecture in CP using DTI and implicates impaired cross-sectional muscle growth in children with cerebral palsy.
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