ArticleCirculation2019
DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy.
Abstract readLetter
In one paragraph
Article in Circulation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed.
- Inflammation, metabolism, and aging in heart failure with preserved ejection fraction: Mechanisms and treatment perspectives.Journal of translational internal medicine · 2026Article
- DNA damage and repair in cardiomyopathy: mechanisms and therapeutic opportunities.American journal of physiology. Heart and circulatory physiology · 2026Review
- Cardiomyocyte-Restricted Expression of Progerin Confers Cardiac Hypertrophy.Circulation research · 2025Article
- Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC-CXCL1-CXCR2 axis.Nature cardiovascular research · 2025Article
- NRF2 activation in the heart induces glucose metabolic reprogramming and reduces cardiac dysfunction via upregulation of the pentose phosphate pathway.Cardiovascular research · 2025Article
- Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by spatial and single-cell transcriptomics.Science advances · 2025Article
- From DNA Repair to Redox Signaling: The Multifaceted Role of APEX1 (Apurinic/Apyrimidinic Endonuclease 1) in Cardiovascular Health and Disease.International journal of molecular sciences · 2025Review
- Long noncoding RNA AK144717 exacerbates pathological cardiac hypertrophy through modulating the cellular distribution of HMGB1 and subsequent DNA damage response.Cellular and molecular life sciences : CMLS · 2024Article
- P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-Derived Cardiomyocytes in 3-Dimensional Suspension Culture Via FOXO-FOXM1 Regulation.Journal of the American Heart Association · 2024Article
- The redox-active defensive Selenoprotein T as a novel stress sensor protein playing a key role in the pathophysiology of heart failure.Journal of translational medicine · 2024Article
- Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage.The journal of cardiovascular aging · 2024Article
- Hypertrophic cardiomyopathy inThe journal of cardiovascular aging · 2024Article
- Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development.Developmental cell · 2023Article
- DNA Damage and Nuclear Morphological Changes in Cardiac Hypertrophy Are Mediated by SNRK Through Actin Depolymerization.Circulation · 2023Article
- DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization.bioRxiv : the preprint server for biology · 2023Article
- Article
- Septal radioablation therapy for patients with hypertrophic obstructive cardiomyopathy: first-in-human study.European heart journal open · 2023Article
- DNA damage response signaling: A common link between cancer and cardiovascular diseases.Cancer medicine · 2023Review
- Metabolic Control of Cardiomyocyte Cell Cycle.Methodist DeBakey cardiovascular journal · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Yuji NakadaDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Ngoc Uyen Nhi NguyenDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Feng XiaoDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Jainy J SavlaDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Nicholas T LamDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Salim AbdisalaamDepartment of Radiation Oncology (S.A., S.B., S.M., A.A.), the University of Texas Southwestern Medical Center, Dallas.
Souparno BhattacharyaDepartment of Radiation Oncology (S.A., S.B., S.M., A.A.), the University of Texas Southwestern Medical Center, Dallas.
Shibani MukherjeeDepartment of Radiation Oncology (S.A., S.B., S.M., A.A.), the University of Texas Southwestern Medical Center, Dallas.
Aroumougame AsaithambyDepartment of Radiation Oncology (S.A., S.B., S.M., A.A.), the University of Texas Southwestern Medical Center, Dallas.
Thomas G GilletteDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Joseph A HillDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Hesham A SadekDepartment of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.
Funding
Oxidative DNA Damage Regulates Cardiomyocyte ProliferationR01HL138983 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SADEK, HESHAM, SZWEDA, LUKE IGNATIUS · 2018 to 2021
$3.1MRole of Meis1 in Regulation of Cardiomyocyte ProliferationR01HL115275 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SADEK, HESHAM · 2012 to 2016
$2.4MMolecular Roles for Werner Syndrome Protein in Replication Fork MaintenanceR01AG053341 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI AROUMOUGAME, ASAITHAMBY · 2016 to 2020
$1.7MRegulation of Cardiomyocyte Turnover in the Adult Mammalian HeartR01HL131778 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SADEK, HESHAM · 2016 to 2019
$1.6MNHLBI NIH HHS R01 HL115275NHLBI NIH HHS R01 HL131778NHLBI NIH HHS R01 HL138983NIA NIH HHS R01 AG053341
Abstract
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Indexed as
Cell CycleDNA DamageAngiotensin IIAnimalsCardiomegalyDisease Models, AnimalMiceMyocytes, CardiacAngiotensin IIangiotensin IIataxia telangiectasia, mutatedDNA damageDNA, double-strandedhypertrophyKU60019myocytes, cardiac
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.