Evidence map›Paper›PMID 30802137›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Direct repression of anoctamin 1 (

Amelia Mazzone, Simon J Gibbons, Seth T Eisenman, Peter R Strege, Tenghao Zheng, Mauro D'Amato, Tamas Ordog, Martin E Fernandez-Zapico, Gianrico Farrugia

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Capsaicin as an amphipathic modulator of NaChannels (Austin, Tex.) · 2022
    Article
  2. Article
  3. Review
  4. Linking neurons to immunity: Lessons fromProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Prototypical pacemaker neurons interact with the resident microbiota.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Amelia MazzoneEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Simon J GibbonsEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Seth T EisenmanEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Peter R StregeEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Tenghao ZhengDepartment of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Mauro D'AmatoDepartment of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Tamas OrdogEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Martin E Fernandez-ZapicoSchulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Gianrico FarrugiaEnteric NeuroSciences, Mayo Clinic, Rochester, Minnesota, USA.
Karolinska Institutet · SEMayo Clinic · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI Nicholas F. LaRusso · 2009 to 2026
$22.2M
CALCIUM DYNAMICS IN INTERSTITIAL CELLS OF CAJALR01DK057061 · NIDDK · MAYO CLINIC ROCHESTER · PI GIANRICO FARRUGIA, Tamas Ordog · 2000 to 2026
$8.2M
Interstitial Cells of Cajal in Diabetic GastropathyR01DK058185 · NIDDK · UNIVERSITY OF NEVADA RENO · PI ORDOG, TAMAS · 2002 to 2020
$5.2M
Mechanism of Pancreatic CarcinogenesisR01CA136526 · NCI · MAYO CLINIC ROCHESTER · PI FERNANDEZ-ZAPICO, MARTIN ERNESTO · 2009 to 2019
$3.0M
NCI NIH HHS R01 CA136526NIDDK NIH HHS P30 DK084567NIDDK NIH HHS R01 DK057061NIDDK NIH HHS R01 DK058185
6 · The paper itself

Abstract

The Ca

Indexed as

Gene Expression RegulationTranscription, GeneticTranscription Initiation SiteAnoctamin-1CalciumCalcium SignalingHEK293 CellsHumansIrritable Bowel SyndromeMutationNeoplasm ProteinsNuclear ProteinsPolymorphism, Single NucleotideZinc Finger Protein GLI1Zinc Finger Protein Gli2ANO1 protein, humanAnoctamin-1CalciumGLI1 protein, humanGLI2 protein, humanNeoplasm ProteinsNuclear ProteinsZinc Finger Protein GLI1Zinc Finger Protein Gli2calcium-activated chloride currentsgastrointestinal traction channelsSNPTMEM16A

Identifiers

PMID30802137
PMCPMC6463924
OpenAlexW2916383821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.