Evidence map›Paper›PMID 30801845›Full record

ArticleGlia2019

G

Caitlin A Durkee, Ana Covelo, Justin Lines, Paulo Kofuji, Juan Aguilar, Alfonso Araque

Open access · greenAbstract read
In one paragraph

Article in Glia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 221 citations in OpenAlex.

  1. [Advances in innate immune-mediated neuroinflammatory mechanisms of migraine].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
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  3. Review
  4. Article
  5. Tanycyte-derived lactate activates astrocytic HCAR1 to modulate glutamatergic signaling and POMC neuron excitability.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Astrocyte Regulation of Spinal Circuit Function.Journal of neurochemistry · 2026
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Astrocytes as Active Participants in Memory.Journal of neurochemistry · 2025
    Review
  17. Article
  18. Review
  19. Review
  20. Article

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Caitlin A DurkeeDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota.
Ana CoveloDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota.
Justin LinesDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota.
Paulo KofujiDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota.
Juan AguilarLaboratory of Experimental Neurophysiology, Hospital Nacional de Parapléjicos, Toledo, Spain.
Alfonso AraqueDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-3840-1144
University of Minnesota · USHospital Nacional de Parapléjicos · ES

Funding

Tau-dependent cognitive deficits in alpha-synucleinopathiesR01NS108686 · NINDS · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO, LEE, MICHAEL K · 2018 to 2022
$2.8M
Astrocyte-neuron interaction in behavior driven by striatal information processingR01NS097312 · NINDS · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO, REDISH, A DAVID · 2016 to 2019
$1.8M
Properties and functional consequences of astrocyte-neuron signaling in the dorsolateral striatumF31NS093751 · NINDS · UNIVERSITY OF MINNESOTA · PI DURKEE, CAITLIN · 2015 to 2017
$117k
Cortical Astrocyte - Neuronal Network Pathophysiology in Alzheimer's Disease In VivoF31AG057155 · NIA · UNIVERSITY OF MINNESOTA · PI LINES, JUSTIN · 2018 to 2020
$82k
NIA NIH HHS F31 AG057155NINDS NIH HHS F31 NS093751NINDS NIH HHS R01 NS097312NINDS NIH HHS R01 NS108686
6 · The paper itself

Abstract

G protein-coupled receptors (GPCRs) play key roles in intercellular signaling in the brain. Their effects on cellular function have been largely studied in neurons, but their functional consequences on astrocytes are less known. Using both endogenous and chemogenetic approaches with DREADDs, we have investigated the effects of G

Indexed as

AnimalsAstrocytesFemaleGTP-Binding Protein alpha Subunits, Gi-GoHippocampusMaleMiceMice, Inbred C57BLMice, TransgenicMuscarinic AntagonistsNeural InhibitionNeurogliaNeuronsOrgan Culture TechniquesReceptors, G-Protein-CoupledGTP-Binding Protein alpha Subunits, Gi-GoMuscarinic AntagonistsReceptors, G-Protein-Coupledastrocyte Ca2+astrocytesDREADDsgliotransmissionG protein-coupled receptors

Identifiers

PMID30801845
PMCPMC6462242
OpenAlexW2915270937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.