Evidence map›Paper›PMID 30801718›Full record

ReviewMedical physics2019

Detection of potential microcalcification clusters using multivendor for-presentation digital mammograms for short-term breast cancer risk estimation.

Maya Alsheh Ali, Mikael Eriksson, Kamila Czene, Per Hall, Keith Humphreys

Open access · hybridAbstract readReview
In one paragraph

Review in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. A Review of Artificial Intelligence in Breast Imaging.Tomography (Ann Arbor, Mich.) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maya Alsheh AliDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-17177, Sweden.
Mikael ErikssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-17177, Sweden.
Kamila CzeneDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-17177, Sweden.
Per HallDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-17177, Sweden.
Keith HumphreysDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-17177, Sweden.
Karolinska Institutet · SE

Funding

PHYSICIAN-INVESTIGATOR DEVELOPMENT AWARD PROGRAMK08CA001245 · NCI · UNIVERSITY OF LOUISVILLE · PI HEUSER, LOUIS S · 1986 to 1986
–
Linneus Centre 70867902Swedish Cancer Society CAN 2017/287Swedish Research Council 2016-01245
6 · The paper itself

Abstract

purposeWe explore using the number of potential microcalcification clusters detected in for-presentation mammographic images (the images which are typically accessible to large epidemiological studies) a marker of short-term breast cancer risk.

methodsWe designed a three-step algorithm for detecting potential microcalcification clusters in for-presentation digital mammograms. We studied association with short-term breast cancer risk using a nested case control design, with a mammography screening cohort as a source population. In total, 373 incident breast cancer cases (diagnosed at least 3 months after a negative screen at study entry) and 1466 matched controls were included in our study. Conditional logistic regression Wald tests were used to test for association with the presence of microcalcifications at study entry. We compared results of these analyses to those obtained using a Computer-aided Diagnosis (CAD) software (VuComp) on corresponding for-processing images (images which are used clinically, but typically not saved).

resultsWe found a moderate agreement between our measure of potential microcalcification clusters on for-presentation images and a CAD measure on for-processing images. Similar evidence of association with short-term breast cancer risk was found (P =

conclusionMeaningful measurement of potential microcalcifications, in the context of short-term breast cancer risk assessment, is feasible for for-presentation images across a range of vendors. Our algorithm for for-presentation images performs similarly to a CAD algorithm on for-processing images, hence our algorithm can be a useful tool for research on microcalcifications and their role on breast cancer risk, based on large-scale epidemiological studies with access to for-presentation images.

Indexed as

Breast NeoplasmsCalcinosisFemaleHumansMammographyRadiographic Image Interpretation, Computer-AssistedRisk FactorsSoftwarebreast cancer riskfor-presentation formatMultivendor full-field digital mammography

Identifiers

PMID30801718
PMCPMC6850331
OpenAlexW2915106800

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.