Evidence map›Paper›PMID 30801053›Full record

ArticlePeptide science (Hoboken, N.J.)2019

Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor.

Grazyna Weltrowska, Thi M-D Nguyen, Nga N Chung, Brian C Wilkes, Peter W Schiller

Abstract read
In one paragraph

Article in Peptide science (Hoboken, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Total synthesis and biological activity of "carbamorphine": O-to-CHProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grazyna WeltrowskaLaboratory of Chemical Biology and Peptide Research, Montreal Clinical Research Institute, 110 Pine Ave. West, Montreal, Quebec, Canada H2W 1R7.
Thi M-D NguyenLaboratory of Chemical Biology and Peptide Research, Montreal Clinical Research Institute, 110 Pine Ave. West, Montreal, Quebec, Canada H2W 1R7.
Nga N ChungLaboratory of Chemical Biology and Peptide Research, Montreal Clinical Research Institute, 110 Pine Ave. West, Montreal, Quebec, Canada H2W 1R7.
Brian C WilkesLaboratory of Chemical Biology and Peptide Research, Montreal Clinical Research Institute, 110 Pine Ave. West, Montreal, Quebec, Canada H2W 1R7.
Peter W SchillerLaboratory of Chemical Biology and Peptide Research, Montreal Clinical Research Institute, 110 Pine Ave. West, Montreal, Quebec, Canada H2W 1R7.

Funding

DEVELOPMENT OF RECEPTOR-SPECIFIC OPIOID PEPTIDE ANALOGSR01DA004443 · NIDA · CLINICAL RESEARCH INSTITUTE OF MONTREAL · PI SCHILLER, PETER W · 1987 to 2016
$2.0M
Gene Therapy And NeuroprotectionZ01DA000443 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI HARVEY, BRANDON · 2001 to 2008
$1.3M
DEVELOPMENT OF RECEPTOR SPECIFIC OPIOID PEPTIDE ANALOGSR37DA004443 · NIDA · CLINICAL RESEARCH INSTITUTE OF MONTREAL · PI SCHILLER, PETER W · 1997 to 2003
$621k
Intramural NIH HHS Z01 DA000443NIDA NIH HHS R01 DA004443NIDA NIH HHS R37 DA004443
6 · The paper itself

Abstract

Head-to-tail cyclized analogues of the μ opioid receptor (MOR) agonist tetrapeptides DALDA (H-Tyr-D-Arg-Phe-Lys-NH

Identifiers

PMID30801053
PMCPMC6383560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.