Evidence map›Paper›PMID 30801050›Full record

ArticleJCO precision oncology2018

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade.

Ian F Dunn, Ziming Du, Mehdi Touat, Michael B Sisti, Patrick Y Wen, Renato Umeton, Adrian M Dubuc, Matthew Ducar, Peter D Canoll, Eric Severson and 9 more

Abstract read
In one paragraph

Article in JCO precision oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
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  7. Review
  8. Review
  9. Cancer stem cells in meningiomas: novel insights and therapeutic implications.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ian F Dunn *Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA.
Ziming Du *Department of Pathology, Brigham and Women's Hospital, Boston, MA.
Mehdi TouatDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Michael B SistiDepartment of Neurosurgery, Columbia University Medical Center, New York City, NY.
Patrick Y WenDepartment of Neurology, Brigham and Women's Hospital, Boston, MA.
Renato UmetonDepartment of Informatics, Dana-Farber Cancer Institute, Boston, MA.
Adrian M DubucDepartment of Pathology, Brigham and Women's Hospital, Boston, MA.
Matthew DucarDepartment of Informatics, Dana-Farber Cancer Institute, Boston, MA.
Peter D CanollDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York City, NY.
Eric SeversonFoundation Medicine, Inc., Morrisville, NC.
Julia A ElvinFoundation Medicine, Inc., Cambridge, MA.
Shakti H RamkissoonFoundation Medicine, Inc., Morrisville, NC.
Jia-Ren LinLudwig Center at Harvard Medical School, Boston, MA.
Lais CabreraCenter for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA.
Brenda AcevedoCenter for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA.
Peter K SorgerLudwig Center at Harvard Medical School, Boston, MA.
Keith L LigonDepartment of Pathology, Brigham and Women's Hospital, Boston, MA.
Sandro Santagata *Department of Pathology, Brigham and Women's Hospital, Boston, MA.
David A Reardon *Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

Funding

Systems Pharmacology of Therapeutic and Adverse Responses to ImmuneCheckpoint and Small Molecule DrugsU54CA225088 · NCI · HARVARD MEDICAL SCHOOL · PI SORGER, PETER KARL · 2018 to 2022
$10.8M
NCI NIH HHS U54 CA225088
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30801050
PMCPMC6383717

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.