Evidence map›Paper›PMID 30800697›Full record

ArticleOpen forum infectious diseases2019

Plasma Profiles of Inflammatory Markers Associated With Active Tuberculosis in Antiretroviral Therapy-Naive Human Immunodeficiency Virus-Positive Individuals.

Oskar Olsson, Per Björkman, Marianne Jansson, Taye Tolera Balcha, Daba Mulleta, Habtamu Yeba, Christine Valfridsson, Fredric Carlsson, Sten Skogmar

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Brief Report: Sex and HIV Modify Immune Activation Biomarkers in Ugandans Post-Tuberculosis.Journal of acquired immune deficiency syndromes (1999) · 2025
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Oskar OlssonDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Malmö, Sweden.ORCID 0000-0002-5106-9222
Per BjörkmanDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Malmö, Sweden.
Marianne JanssonDepartment of Laboratory Medicine, Division of Medical Microbiology, Lund University, Sweden.ORCID 0000-0001-6536-8146
Taye Tolera BalchaDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Malmö, Sweden.
Daba MulletaAdama Regional Laboratory, Ethiopia.
Habtamu YebaAdama Regional Laboratory, Ethiopia.
Christine ValfridssonDepartment of Experimental Medical Science, Section for Immunology, Lund University, Sweden.
Fredric CarlssonDepartment of Experimental Medical Science, Section for Immunology, Lund University, Sweden.
Sten SkogmarDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Malmö, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnosis of tuberculosis (TB) in human immunodeficiency virus (HIV)-coinfected individuals is challenging. We hypothesized that combinations of inflammatory markers could facilitate identification of active TB in HIV-positive individuals.

methodsParticipants were HIV-positive, treatment-naive adults systematically investigated for TB at Ethiopian health centers. Plasma samples from 130 subjects with TB (HIV

resultsThe HIV

conclusionsAlthough CRP showed the best single marker discriminatory potential, combining CRP and suPAR analyses increased performance for TB identification.

Indexed as

biomarkerCRPHIVMycobacterium tuberculosissub-Saharan Africa

Identifiers

PMID30800697
PMCPMC6379652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.