ReviewFrontiers in cellular and infection microbiology2019
An Overview of Peripheral Blood Mononuclear Cells as a Model for Immunological Research of
Review in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Exploratory multi-omics analysis suggests context-dependent immune responses to vitamin DFrontiers in immunology · 2026Article
- Transcriptome profiling of peripheral blood mononuclear cells from highly susceptible adult cattle infected with a virulent strain of Babesia bovis.Parasites & vectors · 2025Article
- Transcriptomic analyses of peripheral blood mononuclear cells reveal age-specific basal and acute exercise responsiveness differences in humans.American journal of physiology. Endocrinology and metabolism · 2025Article
- CRISPRoff epigenome editing for programmable gene silencing in human cell lines and primary T cells.Methods in enzymology · 2025Article
- Cloning, expression, and purification of an α-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2024Article
- CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks.bioRxiv : the preprint server for biology · 2024Article
- Temperature impacts the bovine ex vivo immune response towards Mycoplasmopsis bovis.Veterinary research · 2024Article
- Genetic Variations in the Purinergic P2X7 Receptor Are Associated with the Immune Response to Ocular Toxoplasmosis in Colombia.Microorganisms · 2023Article
- Anti-inflammatory effects of vagus nerve stimulation in pediatric patients with epilepsy.Frontiers in immunology · 2023Article
- Synthetic antioxidants from a natural source can overtake the oncogenic stress management system and activate the stress‑sensitized death of KSHV‑infected cancer cells.International journal of molecular medicine · 2022Article
- Evaluation of Anthelmintic and Anti-Inflammatory Activity of 1,2,4-Triazole Derivatives.Molecules (Basel, Switzerland) · 2022Article
- Regulatory effects of a novel cysteine protease inhibitor in Baylisascaris schroederi migratory larvae on mice immune cells.Parasites & vectors · 2022Article
- Primary Cell Lines From Feathers and Blood of Free-Living Tawny Owls (Strix aluco): A NewFrontiers in genetics · 2022Article
- Current Models to Study theFrontiers in fungal biology · 2022Review
- Anti-Inflammatory Activity of Fucoidan Extracts In Vitro.Marine drugs · 2021Article
- Host transcriptome response to Borrelia burgdorferi sensu lato.Ticks and tick-borne diseases · 2021Review
- The Cytokinesis-Block Micronucleus Assay on Human Isolated Fresh and Cryopreserved Peripheral Blood Mononuclear Cells.Journal of personalized medicine · 2020Article
- Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11.PLoS pathogens · 2020Article
- Profiles of Local and Systemic Inflammation in the Outcome of Treatment of Human Cutaneous Leishmaniasis Caused byInfection and immunity · 2020Article
- Influence of Two MajorFrontiers in cellular and infection microbiology · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In biology, models are experimental systems meant to recreate aspects of diseases or human tissue with the goal of generating inferences and approximations that can contribute to the resolution of specific biological problems. Although there are many models for studying intracellular parasites, their data have produced critical contradictions, especially in immunological assays. Peripheral blood mononuclear cells (PBMCs) represent an attractive tissue source in pharmacogenomics and in molecular and immunologic studies, as these cells are easily collected from patients and can serve as sentinel tissue for monitoring physiological perturbations due to disease. However, these cells are a very sensitive model due to variables such as temperature, type of stimulus and time of collection as part of posterior processes. PBMCs have been used to study
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