Evidence map›Paper›PMID 30800638›Full record

ArticleEuropean thyroid journal2019

Hypofractionated Radiotherapy for Anaplastic Thyroid Carcinoma: 15 Years of Experience in a Single Institution.

Noriyoshi Takahashi, Haruo Matsushita, Rei Umezawa, Takaya Yamamoto, Yojiro Ishikawa, Yu Katagiri, Shun Tasaka, Kazuya Takeda, Katsuya Fukui, Noriyuki Kadoya and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in European thyroid journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. The efficacy of various treatment modalities and their combinations in improving survival outcomes for anaplastic thyroid cancer: a systematic review and network meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Pooled it
  3. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Noriyoshi TakahashiDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Haruo MatsushitaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Rei UmezawaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Takaya YamamotoDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yojiro IshikawaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yu KatagiriDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shun TasakaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kazuya TakedaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Katsuya FukuiDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Noriyuki KadoyaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kengo ItoDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Keiichi JinguDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnaplastic thyroid carcinoma (ATC) is a rare cancer and has a poor prognosis. Several radiation protocols have been reported, but the results were not satisfactory.

objectiveThe aim of this study was to determine the effect of hypofractionated radiotherapy.

methodsThirty-three patients who received radiotherapy for ATC between January 2000 and December 2014 were retrospectively included. We defined hypofractionated radiotherapy as a single dose ≥5 Gy.

resultsNineteen patients were treated with hypofractionated radiotherapy. Twenty-eight patients died, and 27 of those patients died from ATC. Sixteen patients died from distant metastasis and 6 from local recurrence. In the hypofractionated radiotherapy group, local recurrence occurred in 5 patients and 1 of them died from active bleeding from a local tumor. There was local recurrence in 7 patients who received the other protocol, and 5 of them died from asphyxiation, active bleeding, or uncontrollable growth of a local tumor on the neck. The median overall survival (OS) was 5 months. In multivariate analysis, patients who received an equivalent dose in 2-Gy fractions (EQD

conclusionsMultivariate analysis showed that an EQD

Indexed as

Anaplastic thyroid carcinomaHypofractionated radiotherapyRadiation therapyRadiotherapy

Identifiers

PMID30800638
PMCPMC6381908
OpenAlexW2895452837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.