Evidence map›Paper›PMID 30800538›Full record

ArticleCureus2018

Septo-optic Dysplasia Plus Syndrome.

Alejandro Gutierrez-Castillo, Amado Jimenez-Ruiz, Melissa Chavez-Castillo, José Luis Ruiz-Sandoval

Abstract readCase Reports
In one paragraph

Article in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Septo-optic dysplasia plus: A case report for reviewing and recognizing this conditionBiomedica : revista del Instituto Nacional de Salud · 2024
    Review
  4. Article
  5. Article
  6. Primary PCI and Mental Health: A 12-Month Follow-Up Study.Healthcare (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro Gutierrez-CastilloMiscellaneous, Instituto Tecnológico Y De Estudios Superiores De Monterrey, Monterrey, MEX.
Amado Jimenez-RuizNeurology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de Mexico, MEX.
Melissa Chavez-CastilloPediatric Neurology, Instituto Nacional De Pediatría, Mexico City, MEX.
José Luis Ruiz-SandovalNeurology, Hospital Civil De Guadalajara "Fray Antonio Alcalde", Guadalajara, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Septo-optic dysplasia plus is a rare congenital syndrome characterized by the classic triad of optic nerve hypoplasia, hypothalamic-hypophyseal dysfunction, and midline abnormalities, with associated malformations of cortical development. Clinical manifestations include optic nerve disease, epilepsy, intellectual delay, and endocrine dysfunction. We present the case of an 18-year-old man with a history of seizures, growth hormone deficiency, and optic nerve disease that was diagnosed with septo-optic dysplasia plus syndrome with characteristic imaging findings.

Indexed as

cortical dysplasiaepilepsygrowth hormone deficiencyhypoplasia of corpus callosumoptic nerve hypoplasiapolymicrogyriaschizencephalyseizuresepto-optic dysplasiaseptum pellucidum agenesis

Identifiers

PMID30800538
PMCPMC6384050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.