Evidence map›Paper›PMID 30800515›Full record

ArticleBiomedical optics express2019

Simultaneous voltage and calcium imaging and optogenetic stimulation with high sensitivity and a wide field of view.

Cuong Nguyen, Hansini Upadhyay, Michael Murphy, Gabriel Borja, Emily J Rozsahegyi, Adam Barnett, Ted Brookings, Owen B McManus, Christopher A Werley

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Hemodynamic and Electrophysiological Progression of the Rose Bengal Photothrombotic Stroke Model in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  15. Article
  16. Article
  17. Cardiac optogenetics: a decade of enlightenment.Nature reviews. Cardiology · 2021
    Review
  18. Article
  19. Can We Panelize Seizure?Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  20. Imaging Voltage with Microbial Rhodopsins.Frontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cuong NguyenQ-State Biosciences, Cambridge, MA 02139, USA.
Hansini UpadhyayQ-State Biosciences, Cambridge, MA 02139, USA.
Michael MurphyQ-State Biosciences, Cambridge, MA 02139, USA.
Gabriel BorjaQ-State Biosciences, Cambridge, MA 02139, USA.
Emily J RozsahegyiQ-State Biosciences, Cambridge, MA 02139, USA.
Adam BarnettQ-State Biosciences, Cambridge, MA 02139, USA.
Ted BrookingsQ-State Biosciences, Cambridge, MA 02139, USA.
Owen B McManusQ-State Biosciences, Cambridge, MA 02139, USA.
Christopher A WerleyQ-State Biosciences, Cambridge, MA 02139, USA.
Q-State Biosciences (United States) · US

Funding

Optopatch:high-throughput all-optical electrophysiologyR44MH112474 · NIMH · Q-STATE BIOSCIENCES, INC. · PI DEMPSEY, GRAHAM THOMAS, LU, YANG · 2016 to 2020
$3.1M
Scalable, all-optical assays of synaptic function and plasticityR43MH112273 · NIMH · Q-STATE BIOSCIENCES, INC. · PI DEMPSEY, GRAHAM THOMAS, WERLEY, CHRISTOPHER · 2017 to 2018
$765k
NIMH NIH HHS R43 MH112273NIMH NIH HHS R44 MH112474
6 · The paper itself

Abstract

Transmembrane voltage and intracellular calcium concentration are coupled parameters essential to the function of neurons, cardiomyocytes, and other excitable cells. Here we introduce the

Identifiers

PMID30800515
PMCPMC6377900
OpenAlexW2911435322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.