Evidence map›Paper›PMID 30800512›Full record

ArticleBiomedical optics express2019

Comparison of time- and angular-domain scatter rejection in mesoscopic optical projection tomography: a simulation study.

L Sinha, F Massanes, V C Torres, C Li, K M Tichauer, J G Brankov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L SinhaBiomedical Engineering, Illinois Institute of Technology, 3255 South Dearborn Street, Chicago, IL 60616, USA.
F MassanesElectrical and Computer Engineering, Illinois Institute of Technology, 3301 South Dearborn Street, Chicago, IL 60616, USA.
V C TorresBiomedical Engineering, Illinois Institute of Technology, 3255 South Dearborn Street, Chicago, IL 60616, USA.
C LiBiomedical Engineering, Illinois Institute of Technology, 3255 South Dearborn Street, Chicago, IL 60616, USA.
K M TichauerBiomedical Engineering, Illinois Institute of Technology, 3255 South Dearborn Street, Chicago, IL 60616, USA.
J G BrankovElectrical and Computer Engineering, Illinois Institute of Technology, 3301 South Dearborn Street, Chicago, IL 60616, USA.

Funding

Analyzer-based Phase-Contrast Orthopedic ImagingR01EB023969 · NIBIB · ILLINOIS INSTITUTE OF TECHNOLOGY · PI BRANKOV, JOVAN G · 2018 to 2021
$2.1M
NIBIB NIH HHS R01 EB023969
6 · The paper itself

Abstract

Optical imaging offers exquisite sensitivity and resolution for assessing biological tissue in microscopy applications; however, for samples that are greater than a few hundred microns in thickness (such as whole tissue biopsies), spatial resolution is substantially limited by the effects of light scattering. To improve resolution, time- and angular-domain methods have been developed to reject detection of highly scattered light. This work utilizes a modified version of a commonly used Monte Carlo light propagation software package (MCML) to present the first comparison of time- and angular-domain improvements in spatial resolution with respect to varying sample thickness and optical properties (absorption and scattering). Specific comparisons were made at various tissue thicknesses (1-6 mm) assuming either typical (average) soft tissue scattering properties,

Identifiers

PMID30800512
PMCPMC6377887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.