Evidence map›Paper›PMID 30800424›Full record

ArticleJournal of virus eradication2019

Attrition and treatment outcomes among adolescents and youths living with HIV in the Thai National AIDS Program.

Sirinya Teeraananchai, Thanyawee Puthanakit, Stephen J Kerr, Suchada Chaivooth, Sasisopin Kiertiburanakul, Kulkanya Chokephaibulkit, Sorakij Bhakeecheep, Achara Teeraratkul, Matthew Law, Kiat Ruxrungtham

Abstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sirinya TeeraananchaiHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Thanyawee PuthanakitHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Stephen J KerrHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Suchada ChaivoothHIV/AIDS, Tuberculosis and Infectious Diseases Program, National Health Security Office (NHSO), Thailand.
Sasisopin KiertiburanakulFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kulkanya ChokephaibulkitFaculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Sorakij BhakeecheepHIV/AIDS, Tuberculosis and Infectious Diseases Program, National Health Security Office (NHSO), Thailand.
Achara TeeraratkulThailand MOPH-US CDC Collaboration, Nonthaburi, Thailand.
Matthew LawKirby Institute, University of New South Wales, Sydney, Australia.
Kiat RuxrungthamHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are limited data describing the care outcome of youth living with HIV in Asia. We assessed attrition and treatment outcomes among youths with behaviourly acquired HIV (BIY) and adolescents with perinatally acquired HIV (PIY) who initiated antiretroviral treatment (ART) through the National AIDS Program (NAP) in Thailand.

methodsPeople living with HIV aged 10-24 years who initiated antiretroviral therapy (ART) from 2008 to 2013 through the Thai NAP and who were followed up until 2014 were included in the analysis. We assessed youths initiating ART: BIY aged 15-19 years (BIY1) and BIY aged 20-24 (BIY2) compared against PIY aged 10-14 years. Attrition rates (mortality and loss to follow-up [LTFU]) were calculated and potential associations were assessed using Cox regression. Logistic regression was used to assess associations with treatment failure.

resultsOf 11,954 individuals, 9909 (83%) were BIY with a median follow-up of 2.1 years and 17% were PIY with 4.2 years of follow-up. The median baseline CD4 cell count in BIY was higher (190

conclusionYouth with behaviourally acquired HIV aged 15-19 years had poorer retention rates than older BIY and PIY. Targeted interventions for youth are urgently needed to improve overall treatment outcomes.

Indexed as

attritionNational AIDS programThailandyouth

Identifiers

PMID30800424
PMCPMC6362904

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.