Evidence map›Paper›PMID 30800210›Full record

ArticleOxidative medicine and cellular longevity2019

Decreased Nuclear Ascorbate Accumulation Accompanied with Altered Genomic Methylation Pattern in Fibroblasts from Arterial Tortuosity Syndrome Patients.

Csilla E Németh, Zsófia Nemoda, Péter Lőw, Pál Szabó, Erzsébet Z Horváth, Andy Willaert, Annekatrien Boel, Bert L Callewaert, Paul J Coucke, Marina Colombi and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Nuclear and Cytoplasmic Functions of Vitamin C.Chemical research in toxicology · 2020
    Review
  3. Glucose Transport and Transporters in the Endomembranes.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Csilla E NémethDepartment of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest 1094, Hungary.
Zsófia NemodaDepartment of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest 1094, Hungary.
Péter LőwDepartment of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest 1117, Hungary.ORCID 0000-0003-2450-7087
Pál SzabóResearch Centre for Natural Sciences of the Hungarian Academy of Sciences, Budapest 1117, Hungary.
Erzsébet Z HorváthDepartment of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest 1094, Hungary.
Andy WillaertCenter for Medical Genetics, Ghent University, Ghent B-9000, Belgium.
Annekatrien BoelCenter for Medical Genetics, Ghent University, Ghent B-9000, Belgium.
Bert L CallewaertCenter for Medical Genetics, Ghent University, Ghent B-9000, Belgium.
Paul J CouckeCenter for Medical Genetics, Ghent University, Ghent B-9000, Belgium.
Marina ColombiDivision of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia 25123, Italy.
Gábor BánhegyiDepartment of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest 1094, Hungary.ORCID 0000-0001-7559-0066
Éva MargittaiInstitute of Clinical Experimental Research, Semmelweis University, Budapest 1094, Hungary.ORCID 0000-0003-0841-0613
Semmelweis University · HUGhent University Hospital · BEEötvös Loránd University · HUHUN-REN Research Centre for Natural Sciences · HUUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ascorbate requiring Fe

Indexed as

Genome, Human5-MethylcytosineArteriesAscorbic AcidCell NucleusCells, CulturedDNA MethylationEpigenesis, GeneticFibroblastsHumansJoint InstabilityModels, BiologicalPPAR gammaSkin Diseases, GeneticVascular Malformations5-hydroxymethylcytosine5-MethylcytosineAscorbic AcidPPAR gamma

Identifiers

PMID30800210
PMCPMC6360052
OpenAlexW2908671556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.