Evidence map›Paper›PMID 30800169›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

GC/MS-Based Metabolomics Approach to Evaluate the Effect of Jackyakgamcho-Tang on Acute Colitis.

Seung-Ho Seo, Seong-Eun Park, Eun-Ju Kim, Daehwan Youn, Yu-Mi Lee, Soon-Young Lee, So-Hyeon Bok, Dae-Hun Park, Chang-Seob Seo, Sung-Hoon Byun and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Seung-Ho SeoSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Seong-Eun ParkSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Eun-Ju KimSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Daehwan YounSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Yu-Mi LeeSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Soon-Young LeeSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
So-Hyeon BokSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Dae-Hun ParkSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Chang-Seob SeoHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.ORCID 0000-0002-8156-446X
Sung-Hoon ByunDepartment of Oral and Maxillofacial Surgery, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea.
Ki Young JunHanpoong Pharm. Co., Ltd., Wanju 55316, Republic of Korea.
Dae Sung KimHanpoong Pharm. Co., Ltd., Wanju 55316, Republic of Korea.
Chang-Su NaSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.ORCID 0000-0001-5478-649X
Hong-Seok SonSchool of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.ORCID 0000-0002-2102-7785
Dongshin University · KRHanpoong Pharm (South Korea) · KRGyeongsang National University Hospital · KRKorea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to examine the effects of Jackyakgamcho-tang (JGT) on acute colitis. GC/MS-based metabolomics and NGS-based metagenomics were applied to investigate the alteration of metabolites and microbiota in an acute colitis model. The severity of acute colitis symptoms was alleviated by JGT treatment. Induction of colitis and JGT treatment changed compositions of gut microbiota and inflammatory cytokine levels (TNF-

Identifiers

PMID30800169
PMCPMC6360583
OpenAlexW2914417988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.