Evidence map›Paper›PMID 30800151›Full record

ReviewJournal of geriatric cardiology : JGC2019

Atrial fibrillation in the elderly.

Pablo Díez-Villanueva, Fernando Alfonso

Abstract readReview
In one paragraph

Review in Journal of geriatric cardiology : JGC, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clinical characteristics and outcomes of ischemic stroke despite appropriate oral anticoagulation for atrial fibrillation: A systematic review and meta-analysis of real-world studies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  11. Metabolic Inflexibility as a Pathogenic Basis for Atrial Fibrillation.International journal of molecular sciences · 2022
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  15. The cellular mechanobiology of aging: from biology to mechanics.Annals of the New York Academy of Sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pablo Díez-VillanuevaDepartment of Cardiology, Hospital Universitario de la Princesa, Madrid, Spain.
Fernando AlfonsoDepartment of Cardiology, Hospital Universitario de la Princesa, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common arrhythmia in elderly population, with age being one of the most important factors involved in its pathogenesis. Conduction disturbances may be present on the surface electrocardiogram before AF onset in some patients. Once this arrhythmia is diagnosed, antithrombotic therapy is mandatory in most cases, as this is the only treatment that has demonstrated to improve survival. Age increases both the risk of thromboembolic and bleeding complications, while benefits from anticoagulant therapy outweigh that from bleeding in most scenarios, also in very elderly patients. However, elderly patients with AF are often undertreated. Non-vitamin K antagonist oral anticoagulants have emerged as an alternative to vitamin K antagonists, with significant less adverse events and better profile in terms of efficacy and safety. Other conditions related to age should be carefully evaluated in these patients (including frailty, comorbidity and polypharmacy) to ensure an individualized clinical and therapeutic approach.

Indexed as

Antithrombotic therapyAtrial fibrillationFrailtyNon-vitamin K antagonist oral anticoagulantsThe elderly

Identifiers

PMID30800151
PMCPMC6379238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.