Evidence map›Paper›PMID 30800043›Full record

ArticleMolecular syndromology2019

Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.

Roger H Reeves, Jean Delabar, Marie-Claude Potier, Anita Bhattacharyya, Elizabeth Head, Cynthia Lemere, Alain D Dekker, Peter De Deyn, Pablo Caviedes, Mara Dierssen and 1 more

Abstract read
In one paragraph

Article in Molecular syndromology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Down syndrome.Nature reviews. Disease primers · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roger H ReevesJohns Hopkins University School of Medicine, Baltimore, MD.
Jean DelabarBrain and Spine Institute, Paris, France.
Marie-Claude PotierBrain and Spine Institute, Paris, France.
Anita BhattacharyyaWaisman Center, University of Wisconsin-Madison, Madison, WI.
Elizabeth HeadSanders Brown Center on Aging, University of Kentucky, Lexington, KY.
Cynthia LemereHarvard Medical School, Boston, MA.
Alain D DekkerUniversity of Groningen and University Medical Center, Groningen, The Netherlands.
Peter De DeynUniversity of Groningen and University Medical Center, Groningen, The Netherlands.
Pablo CaviedesFaculty of Medicine, University of Chile, Santiago, Chile.
Mara DierssenCenter for Genomic Regulation, Barcelona, Spain.
Jorge BusciglioUniversity of California-Irvine, Irvine, CA, USA.

Funding

2nd International Conference of the Trisomy 21 Research SocietyR13NS100380 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BUSCIGLIO, JORGE A · 2016 to 2016
$18k
NINDS NIH HHS R13 NS100380
6 · The paper itself

Abstract

In the last decade, a number of important research advances in different fields have allowed Down syndrome (DS) research to flourish, creating a time of both unparalleled opportunity and considerable challenge. Building a scientific framework that distills mechanisms involved in the developmental intellectual disability of DS as well as the early-onset component of Alzheimer disease and the several other comorbidities associated with the condition is a challenge that scientists are now tackling using novel technologies and multidisciplinary approaches. The Trisomy 21 Research Society (T21RS) was founded in 2014 to address these evolving needs and challenges. In June of 2017, the T21RS held its 2nd International Conference in Chicago, USA. With more than 200 scientists, advocates, people with DS, and family members in attendance, the meeting served as a forum for the discussion of the latest research and clinical advances as well as the most compelling needs of people with DS and their families.

Indexed as

Alzheimer diseaseDown syndromeTrisomy 21 Research Society

Identifiers

PMID30800043
PMCPMC6381890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.