Evidence map›Paper›PMID 30799976›Full record

ArticleBiochemia medica2019

Faecal calprotectin determination: impact of preanalytical sample treatment and stool consistency on within- and between-method variability.

Gordana Juricic, Tina Brencic, Andrea Tesija-Kuna, Milena Njegovan, Lorena Honovic

Open access · diamondAbstract read
In one paragraph

Article in Biochemia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Calprest ELISA vs. LiaisonBiomedicines · 2026
    Article
  3. Article
  4. Faecal calprotectin in primary care: is its current use supported by the evidence?The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gordana JuricicDepartment of Laboratory Diagnostics, General Hospital Pula, Pula, Croatia.
Tina BrencicDepartment of Laboratory Diagnostics, General Hospital Pula, Pula, Croatia.
Andrea Tesija-KunaDepartment of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Milena NjegovanDepartment of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Lorena HonovicDepartment of Laboratory Diagnostics, General Hospital Pula, Pula, Croatia.
Juraj Dobrila University of Pula · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe assessed the differences in faecal calprotectin (FC) concentrations measured by two assays depending on the stool consistency and extraction method. MATERIALS AND

methodsStool samples were extracted using the EliA Stool Extraction Kit, Calex® Cap extraction device and respective weighing methods, while FC concentrations were measured using the EliA

resultsResults determined from Calex® Cap extracts were higher compared to weighing method extracts (mean bias 33.3%; P < 0.001), while no significant difference was found between results obtained with EliA Stool Extraction Kit and weighing method (mean bias 0.1%; P = 0.484), in both cases irrespective of stool consistency. Bühlmann fCAL® Turbo results were higher than EliA

conclusionPreanalytical stool sample handling proved to be a crucial factor contributing to within- and between-FC assay variability. Standardization is urgently needed in order to assure comparable and reliable FC results.

Indexed as

Specimen HandlingFecesHumansLeukocyte L1 Antigen ComplexLeukocyte L1 Antigen Complexcalprotectinimmunoassayinflammatory bowel diseasepreanalytical phase

Identifiers

PMID30799976
PMCPMC6366951
OpenAlexW2913181885

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.