Evidence map›Paper›PMID 30799307›Full record

ArticleAging2019

Pleiotropic effect of common

Jinglu Zhao, Yun Zhu, Xiaoli Xie, Yuxiao Yao, Jiao Zhang, Ruizhong Zhang, Lihua Huang, Jiwen Cheng, Huimin Xia, Jing He and 1 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Refining the Sox10Animal models and experimental medicine · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Negative Association Between lncRNAPharmacogenomics and personalized medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jinglu Zhao *Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Yun Zhu *Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Xiaoli Xie *Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Yuxiao YaoDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Jiao ZhangDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzho, Henan 450052, China.
Ruizhong ZhangDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Lihua HuangDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Jiwen ChengDepartment of Pediatric Surgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'a, Shaanxi 710004, China.
Huimin XiaDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Jing HeDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Yan ZhangDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzho, Guangdong 510623, China.
Guangzhou Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hirschsprung disease (HSCR) is a heterogeneous congenital disorder that affects the enteric nervous system, while neuroblastoma is an embryonal tumor of the sympathetic nervous system. Familial cases of both HSCR and neuroblastoma appear to be functionally linked to

Indexed as

Genetic Predisposition to DiseasePolymorphism, GeneticCase-Control StudiesFemaleHirschsprung DiseaseHomeodomain ProteinsHumansInfantInfant, NewbornMaleNeuroblastomaTranscription FactorsHomeodomain ProteinsNBPhox proteinTranscription FactorsHirschsprung’s diseaseneuroblastomaPHOX2Bpleiotropic effect

Identifiers

PMID30799307
PMCPMC6402522
OpenAlexW2916099678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.