ArticleAnnals of epidemiology2019
Perceived stress and incident sexually transmitted infections in a prospective cohort.
Article in Annals of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed.
- Social, microbial, and immune factors linking bacterial vaginosis and infectious diseases.The Journal of clinical investigation · 2025Review
- HIV and Viremia Prevalence in Nonmigrating Members of Migrant Households in Southern Uganda: A Cross-Sectional Population-Based Study.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- HIV incidence among non-migrating persons following a household migration event in Uganda.International journal of epidemiology · 2024Article
- Article
- Characterization of beta2-adrenergic receptor knockout mouse model during Chlamydia muridarum genital infection.Pathogens and disease · 2024Article
- Integrating compositional and functional content to describe vaginal microbiomes in health and disease.Microbiome · 2023Article
- Advances in Research on the Relationship between Vaginal Microbiota and Adverse Pregnancy Outcomes and Gynecological Diseases.Microorganisms · 2023Review
- Scoping review of the association between bacterial vaginosis and emotional, sexual and social health.BMC women's health · 2023Article
- Puberty- and Menstruation-Related Stressors Are Associated with Depression, Anxiety, and Reproductive Tract Infection Symptoms Among Adolescent Girls in Tanzania.International journal of behavioral medicine · 2022Article
- Incarceration and Subsequent Pregnancy Loss: Exploration of Sexually Transmitted Infections as Mediating Pathways.Journal of women's health (2002) · 2022Article
- Perceived Stress and Molecular Bacterial Vaginosis in the National Institutes of Health Longitudinal Study of Vaginal Flora.American journal of epidemiology · 2021Article
- What Racism Has to Do with It: Understanding and Reducing Sexually Transmitted Diseases in Youth of Color.Healthcare (Basel, Switzerland) · 2021Review
- Intimate Partner Violence, Depression, and Anxiety Are Associated With Higher Perceived Stress Among Both Young Men and Women in Soweto and Durban, South Africa.Frontiers in reproductive health · 2021Article
- Vaginal microbiota of American Indian women and associations with measures of psychosocial stress.PloS one · 2021Article
- Characterization of Vaginal Microbiota in Women With Recurrent Spontaneous Abortion That Can Be Modified by Drug Treatment.Frontiers in cellular and infection microbiology · 2021Article
- Perceived Stress, Sexually Transmitted Infection, and Pelvic Inflammatory Disease: Examination of Differences in Associations Among Black and White Women.Sexually transmitted diseases · 2020Article
- How the evolving epidemics of opioid misuse and HIV infection may be changing the risk of oral sexually transmitted infection risk through microbiome modulation.Critical reviews in microbiology · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposePsychosocial stress has been associated with susceptibility to many infectious pathogens. We evaluated the association between perceived stress and incident sexually transmitted infections (STIs; Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis genital infections) in a prospective study of women. Stress may increase vulnerability to STIs by suppressing immune function and altering the protective vaginal microbiota.
methodsUsing the 1999 Longitudinal Study of Vaginal Flora (n = 2439), a primarily African American cohort of women, we fitted Cox proportional hazards models to examine the association between perceived stress and incident STIs. We tested bacterial vaginosis (measured by Nugent Score) and sexual behaviors (condom use, number of partners, and partner concurrence) as mediators using VanderWeele's difference method.
resultsBaseline perceived stress was associated with incident STIs both before and after adjusting for confounders (adjusted hazard ratio = 1.015; 95% confidence interval, 1.005-1.026). Nugent score and sexual behaviors significantly mediated 21% and 65% of this adjusted association, respectively, and 78% when included together in the adjusted model.
conclusionsThis study advances understanding of the relationship between perceived stress and STIs and identifies high-risk sexual behaviors and development of bacterial vaginosis-both known risk factors for STIs-as mechanisms underlying this association.
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