ArticleAnnals of epidemiology2019
Association of secondhand tobacco smoke exposure during childhood on adult cardiovascular disease risk among never-smokers.
Article in Annals of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Secondhand tobacco exposure and risk of atrial fibrillation: a systematic review.BMC public health · 2026Pooled it
- Special Issue "New Trends in Diabetes, Hypertension and Cardiovascular Diseases: 3rd Edition".International journal of molecular sciences · 2025Article
- Risk factors for pediatric ischemic stroke and intracranial hemorrhage: A national electronic health record based study.Heliyon · 2024Article
- Involuntary tobacco smoke exposures from conception to 18 years increase midlife cardiometabolic disease risk: a 40-year longitudinal study.Journal of developmental origins of health and disease · 2023Article
- Effects of Secondhand Smoke Exposure on Children's Future Health.Journal of atherosclerosis and thrombosis · 2023Article
- Trends in Exposure to Secondhand Smoke Among Adolescents in China From 2013-2014 to 2019: Two Repeated National Cross-sectional Surveys.JMIR public health and surveillance · 2023Article
- Status and correlates of children's exposure to secondhand smoke at home: A survey in Chongqing, China.Tobacco induced diseases · 2023Article
- Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa.Journal of the neurological sciences · 2022Article
- Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke.International journal of molecular sciences · 2022Review
- Risk Assessment of Passive Smoking Based on Analysis of Hair Nicotine and Cotinine as Exposure Biomarkers by In-Tube Solid-Phase Microextraction Coupled On-Line to LC-MS/MS.Molecules (Basel, Switzerland) · 2021Article
- Asking the Right Questions About Secondhand Smoke.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Article
- Letter to the Editor: Childhood Secondhand Smoke Exposure and Risk of Dementia in Adulthood.The journal of prevention of Alzheimer's disease · 2021Article
- The Perinatal Condition Around Birth and Cardiovascular Risk Factors in the Japanese General Population: The Suita Study.Journal of atherosclerosis and thrombosis · 2020Article
- Environmental tobacco smoke (ETS) and hyperlipidemia modified by perceived work stress.PloS one · 2020Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
purposeAdult secondhand tobacco smoke (SHS) exposure is related to stroke and coronary heart disease (CHD) risk, but long-term effects are less clear. We evaluated whether childhood SHS exposure affects subsequent stroke or CHD risk among adult black and white never-smokers followed for stroke and CHD.
methodsIn this prospective cohort study, inverse probability weights were calculated to correct for bias due to attrition and survey nonresponse. Cox proportional hazards models were used to assess hazard ratios and 95% confidence intervals for stroke or CHD, separately, by number of childhood household smokers.
resultsOf 13,142 eligible participants, 6136 had childhood SHS exposure assessed. Baseline mean (SD) age was 63.5 (9.0), 65% were female, 30% black, 46% reported 0 childhood household smokers, 36% reported 1, and 18% reported 2+. In 60,649 person-years, 174 strokes were observed (2.9% of participants), and in 45,195 person-years, 114 CHD events were observed (2.1% of participants). The weighted and adjusted hazard ratios (95% confidence intervals) of stroke for 2+ versus 0 childhood household smokers was 1.66 (1.29-2.13) and was 1.15 (0.82-1.59) for CHD.
conclusionsWe observed a significant association between childhood SHS exposure and stroke, but not CHD, after age 45 years and adjusting for missing information.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.