Evidence map›Paper›PMID 30798789›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019

Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation.

Mari Nieves Velasco Forte, Israel Valverde, Nanda Prabhu, Teresa Correia, Srinivas Ananth Narayan, Aaron Bell, Sujeev Mathur, Reza Razavi, Tarique Hussain, Kuberan Pushparajah and 1 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Mari Nieves Velasco ForteDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Israel ValverdeDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Nanda PrabhuDepartment of Congenital Heart Disease, Evelina London Children's Hospital, Guy's and St Thomas NHS Foundation Trust, London, UK.
Teresa CorreiaDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Srinivas Ananth NarayanDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Aaron BellDepartment of Congenital Heart Disease, Evelina London Children's Hospital, Guy's and St Thomas NHS Foundation Trust, London, UK.
Sujeev MathurDepartment of Congenital Heart Disease, Evelina London Children's Hospital, Guy's and St Thomas NHS Foundation Trust, London, UK.
Reza RazaviDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Tarique HussainDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Kuberan PushparajahDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Markus HenningssonDivision of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. markus.henningsson@kcl.ac.uk.
Guy's and St Thomas' NHS Foundation Trust · GBKing's College London · GBHospital Universitario Virgen del Rocío · ESThe University of Texas Southwestern Medical Center · USUniversidad de Sevilla · ES

Funding

British Heart Foundation RE/08/03Department of HealthWellcome TrustWellcome Trust WT 088641/Z/09/Z
6 · The paper itself

Abstract

aimsTo investigate the use of respiratory motion compensation using image-based navigation (iNAV) with constant respiratory efficiency using single end-expiratory thresholding (CRUISE) for coronary magnetic resonance angiography (CMRA), and compare it to the conventional diaphragmatic navigator (dNAV) in paediatric patients with congenital or suspected heart disease.

methodsiNAV allowed direct tracking of the respiratory heart motion and was generated using balanced steady state free precession startup echoes. Respiratory gating was achieved using CRUISE with a fixed 50% efficiency. Whole-heart CMRA was acquired with 1.3 mm isotropic resolution. For comparison, CMRA with identical imaging parameters were acquired using dNAV. Scan time, visualization of coronary artery origins and mid-course, imaging quality and sharpness was compared between the two sequences.

resultsForty patients (13 females; median weight: 44 kg; median age: 12.6, range: 3 months-17 years) were enrolled. 25 scans were performed in awake patients. A contrast agent was used in 22 patients. The scan time was significantly reduced using iNAV for awake patients (iNAV 7:48 ± 1:26 vs dNAV 9:48 ± 3:11, P = 0.01) but not for patients under general anaesthesia (iNAV = 6:55 ± 1:50 versus dNAV = 6:32 ± 2:16; P = 0.32). In 98% of the cases, iNAV image quality had an equal or higher score than dNAV. The visual score analysis showed a clear difference, favouring iNAV (P = 0.002). The right coronary artery and the left anterior descending vessel sharpness was significantly improved (iNAV: 56.8% ± 10.1% vs dNAV: 53.7% ± 9.9%, P < 0.002 and iNAV: 55.8% ± 8.6% vs dNAV: 53% ± 9.2%, P = 0.001, respectively).

conclusioniNAV allows for a higher success-rate and clearer depiction of the mid-course of coronary arteries in paediatric patients. Its acquisition time is shorter in awake patients and image quality score is equal or superior to the conventional method in most cases.

Indexed as

Magnetic Resonance AngiographyMagnetic Resonance Imaging, CineRespirationAdolescentArtifactsChildChild, PreschoolContrast MediaCoronary VesselsFemaleHeart Defects, CongenitalHumansInfantMaleMeglumineOrganometallic CompoundsContrast Mediagadobutrolgadoterate meglumineMeglumineOrganometallic CompoundsCoronary artery diseaseCoronary magnetic resonance angiographyImage-based navigationRespiratory motion compensation

Identifiers

PMID30798789
PMCPMC6388473
OpenAlexW2942984282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.