Evidence map›Paper›PMID 30798607›Full record

ArticleJournal of medicinal chemistry2019

β-Lactones: A Novel Class of Ca

Christina Dedaki, Maroula G Kokotou, Varnavas D Mouchlis, Dimitris Limnios, Xiaoyong Lei, Carol T Mu, Sasanka Ramanadham, Victoria Magrioti, Edward A Dennis, George Kokotos

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Christina DedakiLaboratory of Organic Chemistry, Department of Chemistry , National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771 , Greece.
Maroula G KokotouLaboratory of Organic Chemistry, Department of Chemistry , National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771 , Greece.
Varnavas D MouchlisDepartment of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California, San Diego , La Jolla, San Diego , California 92093-0601 , United States.ORCID 0000-0002-4235-1867
Dimitris LimniosLaboratory of Organic Chemistry, Department of Chemistry , National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771 , Greece.
Xiaoyong Lei
Carol T MuDepartment of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California, San Diego , La Jolla, San Diego , California 92093-0601 , United States.
Sasanka Ramanadham
Victoria MagriotiLaboratory of Organic Chemistry, Department of Chemistry , National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771 , Greece.
Edward A DennisDepartment of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California, San Diego , La Jolla, San Diego , California 92093-0601 , United States.
George KokotosLaboratory of Organic Chemistry, Department of Chemistry , National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771 , Greece.ORCID 0000-0003-3753-7082
National and Kapodistrian University of Athens · GRUniversity of California San Diego · USUniversity of Alabama at Birmingham · US

Funding

ACTION OF LIPOLYTIC ENZYMESR01GM020501 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 1985 to 2020
$7.3M
Contribution of β-Cell- & Immune Cell-Derived Lipids to β-Cell Death and DiabetesR01DK110292 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RAMANADHAM, SASANKA · 2016 to 2019
$1.7M
NIDDK NIH HHS R01 DK110292NIGMS NIH HHS R01 GM020501
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsApoptosisCytokinesDrug DesignHumansInflammation MediatorsInsulin-Secreting CellsLactonesPhospholipase A2 InhibitorsPhospholipases A2, Calcium-IndependentStructure-Activity RelationshipCytokinesInflammation MediatorsLactonesPhospholipase A2 InhibitorsPhospholipases A2, Calcium-Independent

Identifiers

PMID30798607
PMCPMC6767909
OpenAlexW2915330560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.