Evidence map›Paper›PMID 30798418›Full record

ArticleWorld journal of surgery2019

Timing of Parathyroidectomy Does Not Influence Renal Function After Kidney Transplantation.

Willemijn Y van der Plas, Mostafa El Moumni, Philipp J von Forstner, Ezra Y Koh, Roderick R Dulfer, Tessa M van Ginhoven, Joris I Rotmans, Natasha M Appelman-Dijkstra, Abbey Schepers, Ewout J Hoorn and 8 more

Open access · hybridAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Pre-Transplant Hyperparathyroidism and Graft or Patient Outcomes After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Willemijn Y van der PlasDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Mostafa El MoumniDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Philipp J von ForstnerDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ezra Y KohDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Roderick R DulferDepartment of Surgery, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
Tessa M van GinhovenDepartment of Surgery, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
Joris I RotmansDepartment of Nephrology, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
Natasha M Appelman-DijkstraDepartment of Endocrinology, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
Abbey SchepersDepartment of Surgery, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
Ewout J HoornDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
John Th M PlukkerDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Liffert VogtDepartment of Nephrology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Anton F EngelsmanDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Els J M Nieveen van DijkumDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Schelto KruijffDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Robert A PolDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Martin H de BorstDivision of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. m.h.de.borst@umcg.nl.
Dutch Hyperparathyroidism Study Group
University of Groningen · NLLeiden University Medical Center · NLUniversity Medical Center Groningen · NLAmsterdam University Medical Centers · NLErasmus University Rotterdam · NLAmsterdam Neuroscience · NLErasmus MC · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParathyroidectomy (PTx) is the treatment of choice for end-stage renal disease (ESRD) patients with therapy-resistant hyperparathyroidism (HPT). The optimal timing of PTx for ESRD-related HPT-before or after kidney transplantation (KTx)-is subject of debate.

methodsPatients with ESRD-related HPT who underwent both PTx and KTx between 1994 and 2015 were included in a multicenter retrospective study in four university hospitals. Two groups were formed according to treatment sequence: PTx before KTx (PTxKTx) and PTx after KTx (KTxPTx). Primary endpoint was renal function (eGFR, CKD-EPI) between both groups at several time points post-transplantation. Correlation between the timing of PTx and KTx and the course of eGFR was assessed using generalized estimating equations (GEE).

resultsThe PTxKTx group consisted of 102 (55.1%) and the KTxPTx group of 83 (44.9%) patients. Recipient age, donor type, PTx type, and pre-KTx PTH levels were significantly different between groups. At 5 years after transplantation, eGFR was similar in the PTxKTx group (eGFR 44.5 ± 4.0 ml/min/1.73 m

conclusionsIn this multicenter cohort study, timing of PTx before or after KTx does not independently impact graft function over time.

Indexed as

Kidney TransplantationParathyroidectomyAdultAllograftsFemaleFollow-Up StudiesGlomerular Filtration RateHumansHyperparathyroidismKidneyKidney Failure, ChronicMaleMiddle AgedRetrospective StudiesTime Factors

Identifiers

PMID30798418
OpenAlexW2915904682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.