Evidence map›Paper›PMID 30797650›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2019

Engagement in Socially and Interpersonally Rewarding Activities as a Predictor of Outcome in "Engage" Behavioral Activation Therapy for Late-Life Depression.

Nili Solomonov, Jennifer N Bress, Jo Anne Sirey, Faith M Gunning, Christoph Flückiger, Patrick J Raue, Patricia A Areán, George S Alexopoulos

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. A Pilot Randomized Trial of Engage Psychotherapy to Increase Social Connection and Reduce Suicide Risk in Later Life.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Trial
  5. Perceived Social Support and Interpersonal Functioning as Predictors of Treatment Response Among Depressed Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Trial
  6. Trial
  7. Resting State Functional Connectivity and Outcomes of Psychotherapies for Late-Life Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020
    Trial
  8. Targeting mechanisms of change as a path to precision psychotherapy for community settings.Psychotherapy research : journal of the Society for Psychotherapy Research · 2026
    Article
  9. Remission is insufficient: predictors and mechanistic models of recurrence in late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  10. Engage & connect psychotherapy improves social reward responsivity and reduces postpartum depression.Psychotherapy research : journal of the Society for Psychotherapy Research · 2025
    Article
  11. Article
  12. Article
  13. The 5D indicators of suicide risk in older adults who are lonely.Annals of the New York Academy of Sciences · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nili SolomonovWeill Cornell Institute of Geriatric Psychiatry (NS, JNB, JAS, FMG, GSA), Weill Cornell Medicine, White Plains, NY. Electronic address: nis2051@med.cornell.edu.
Jennifer N BressWeill Cornell Institute of Geriatric Psychiatry (NS, JNB, JAS, FMG, GSA), Weill Cornell Medicine, White Plains, NY.
Jo Anne SireyWeill Cornell Institute of Geriatric Psychiatry (NS, JNB, JAS, FMG, GSA), Weill Cornell Medicine, White Plains, NY.
Faith M GunningWeill Cornell Institute of Geriatric Psychiatry (NS, JNB, JAS, FMG, GSA), Weill Cornell Medicine, White Plains, NY.
Christoph FlückigerPsychologisches Institut (CF), University of Zurich, Zurich, Switzerland.
Patrick J RaueDepartment of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington School of Medicine, Seattle.
Patricia A AreánDepartment of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington School of Medicine, Seattle.
George S AlexopoulosWeill Cornell Institute of Geriatric Psychiatry (NS, JNB, JAS, FMG, GSA), Weill Cornell Medicine, White Plains, NY.
Weill Cornell Medicine · USCornell University · USUniversity of Washington · USUniversity of Zurich · CH

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Efficacy of biomarker-guided rTMS for treatment resistant depressionR01MH118388 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI BHATI, MAHENDRA T, GUNNING, FAITH M · 2019 to 2025
$6.2M
Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SIREY, JO ANNE · 2017 to 2020
$5.7M
RESEARCH TRAINING IN GERIATRIC MOOD DISORDERST32MH019132 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUNNING, FAITH M · 1990 to 2025
$3.4M
Target engagement of a reward exposure therapy (Engage) for late life depressionR01MH102252 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2014 to 2018
$2.0M
NCATS NIH HHS UL1 TR002384NIMH NIH HHS P50 MH113838NIMH NIH HHS R01 MH102252NIMH NIH HHS R01 MH118388NIMH NIH HHS T32 MH019132
6 · The paper itself

Abstract

objectiveLoneliness and social isolation are associated with depressive symptoms, cognitive and physical disabilities, and increased risk of mortality among older adults. Socially rewarding activities reduce loneliness, and neurobiological evidence suggests that these activities may activate neural reward systems in older adults to a greater extent than other rewarding experiences. The current study was designed to investigate whether engagement in social and interpersonal activities (i.e., exposure to social rewards) predicts subsequent increase in behavioral activation and reduction in depressive symptoms in reward exposure treatment for late-life depression.

methodsForty-eight older adults without cognitive impairment and with major depression received nine sessions of "Engage" psychotherapy. Behavioral activation and depression severity were assessed by trained raters at baseline and weeks 6 and 9. Patients' weekly behavioral plans were categorized into three groups: 1) solitary activities; 2) social-group activities (attending a social gathering or a social setting such as church or a senior center); and 3) interpersonal-individual activities (engaging in an interpersonal interaction with a specific friend or family member).

resultsMixed-effects models showed reduction in depression severity and increase in behavioral activation over time. In linear regression models, a higher percentage of interpersonal-individual activities (but not solitary or social-group activities) predicted subsequent increase in behavioral activation and improvement of depression.

conclusionThese findings highlight the importance of understanding the effects of engagement in specific types of rewarding activities in behavioral activation treatments for late-life depression. Exposure to socially rewarding interpersonal interactions could contribute to the efficacy of psychotherapy for late-life depression.

Indexed as

Outcome Assessment, Health CareRewardAgedAged, 80 and overBehavior TherapyFemaleHumansMajor Depressive DisorderMaleMiddle AgedSan FranciscoSocial Behaviorbehavioral activationEngageinterpersonal activitiesLate-life depressionpsychotherapysocial reward

Identifiers

PMID30797650
PMCPMC6511287
OpenAlexW2909701478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.