ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2019
Prevalence, Trajectory, and Predictors of Poststroke Fatigue among Ghanaians.
Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Related risk factors associated with post-stroke fatigue: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- A latent transition analysis of longitudinal stability of post-stroke fatigue.Social psychiatry and psychiatric epidemiology · 2026Article
- Trajectories of post-stroke fatigue and its influencing factors in young and middle-aged patients with intracerebral hemorrhage.Frontiers in neurology · 2026Article
- Fatigue after pulmonary embolism-prevalence and predictors.Frontiers in cardiovascular medicine · 2026Article
- Distinct Trajectories of Fatigue Among Families with Post-Intensive Care Syndrome.International journal of general medicine · 2025Article
- The impact of post-stroke fatigue on inpatient rehabilitation outcomes: An observational study.PloS one · 2024Observational
- Early poststroke clinically significant fatigue predicts functional independence: a prospective longitudinal study.Frontiers in neurology · 2024Article
- Relationships between Self-Efficacy and Post-Stroke Activity Limitations, Locomotor Ability, Physical Activity, and Community Reintegration in Sub-Saharan Africa: A Cross-Sectional Study.International journal of environmental research and public health · 2023Article
- Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Article
- The relationship between red blood cell distribution width at admission and post-stroke fatigue in the acute phase of acute ischemic stroke.Frontiers in neurology · 2022Article
- Prevalence of fatigue after stroke: A systematic review and meta-analysis.European stroke journal · 2021Review
- Stroke in Africa: profile, progress, prospects and priorities.Nature reviews. Neurology · 2021Review
- Understanding Why Post-Stroke Depression May Be the Norm Rather Than the Exception: The Anatomical and Neuroinflammatory Correlates of Post-Stroke Depression.Journal of clinical medicine · 2021Review
- Contribution of sleep quality to fatigue following a stroke: a cross-sectional study.BMC neurology · 2021Article
- Serum cystatin C was a marker of poststroke fatigue in hypertensive intracerebral hemorrhage.Brain and behavior · 2021Article
- Antecedent febrile illness and occurrence of stroke in West Africa: The SIREN study.Journal of the neurological sciences · 2020Article
- Low blood pressure levels & incident stroke risk among elderly Ghanaians with hypertension.Journal of the neurological sciences · 2020Article
- Vascular-brain Injury Progression after Stroke (VIPS) study: concept for understanding racial and geographic determinants of cognitive decline after stroke.Journal of the neurological sciences · 2020Review
- Unraveling the risk factors for spontaneous intracerebral hemorrhage among West Africans.Neurology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
background and purposePoststroke fatigue (PSF) is rife among stroke survivors and it exerts a detrimental toll on recovery from functional deficits. The burden of PSF is unknown in sub-Saharan Africa. We have assessed the prevalence, trajectory, and predictors of PSF among 60 recent Ghanaian stroke patients.
methodsStudy participants in this prospective cohort (recruited between January 2017 and June 2017) were stroke survivors, aged greater than 18 years, with CT scan confirmed stroke of less than 1-month onset. PSF was assessed using the Fatigue Severity Scale (FSS) at enrollment, months 3, 6, and 9. Those with a score of greater than or equal to 4 points on FSS were categorized as "fatigued." A multivariate logistic regression analysis was performed to identify independent predictors of PSF at enrollment and at month 9.
resultsSixty-five percent (65%) of our sample were males with a mean age of 55.1 ± 12.7 years. In addition to all participants having hypertension, 85% had dyslipidemia and 25% had diabetes mellitus. Ischemic strokes comprised 76.6% of the study population. The prevalence of PSF was 58.9% at baseline and declined to 23.6% at month 9, P = .0002. Diabetes mellitus was significantly associated with PSF at baseline with an adjusted odds ratio of 15.12 (95% CI: 1.70-134.30), P = .01. However, at month 9, age greater than or equal to 65 years, adjusted odds ratio (aOR) of 7.02 (95% CI: 1.16-42.52); female sex, aOR of 8.52 (1.23-59.16), and depression, aOR of 8.86 (1.19-65.88) were independently associated with PSF.
conclusionsApproximately 6 out of 10 Ghanaian stroke survivors experience PSF within the first month of stroke onset. PSF persists in approximately 1 out of 4 stroke survivors at 10 months after the index stroke. Further studies to elucidate the underlying mechanisms for PSF are required and adequately powered interventional multicenter trials are eagerly awaited to provide solid evidence base for the clinical management of PSF.
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